INT50339

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Context Info
Confidence 0.21
First Reported 1995
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 3
Disease Relevance 2.43
Pain Relevance 0.17

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

fa (Mus musculus)
Pain Link Frequency Relevance Heat
Inflammation 27 96.84 Very High Very High Very High
Bile 6 68.96 Quite High
cINOD 1 50.48 Quite High
alcohol 8 39.68 Quite Low
Bioavailability 4 11.52 Low Low
Nicotine 4 5.00 Very Low Very Low Very Low
Inflammatory mediators 4 5.00 Very Low Very Low Very Low
cytokine 2 5.00 Very Low Very Low Very Low
Pain 2 5.00 Very Low Very Low Very Low
chemokine 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Death 4 99.72 Very High Very High Very High
INFLAMMATION 32 96.84 Very High Very High Very High
Infection 1 92.16 High High
Stress 34 91.84 High High
Neurodegenerative Disease 8 89.40 High High
Disorder Of Lipid Metabolism 2 87.24 High High
Disease 20 86.04 High High
Injury 8 83.84 Quite High
Aging 8 82.64 Quite High
Coronary Heart Disease 6 82.56 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
These data suggest that FA and IFA are novel and potent inhibitors of murine IL-8 production and might act as one of the main components of anti-inflammatory rhizoma of Cimicifuga species.
Negative_regulation (inhibitors) of FA associated with inflammation
1) Confidence 0.21 Published 1995 Journal Planta Med. Section Abstract Doc Link 7617763 Disease Relevance 0.43 Pain Relevance 0.10
Hiramatsu et al. [74], reported that FA and its steryl esters, ?
Negative_regulation (reported) of FA
2) Confidence 0.03 Published 2007 Journal Journal of Clinical Biochemistry and Nutrition Section Body Doc Link PMC2127228 Disease Relevance 0.90 Pain Relevance 0
FA is reported as a potent scavenger of ROS and RNS and thereby reduces the chance of free radical attack on proteins and hence preventing their oxidative modification [53].
Negative_regulation (reduces) of FA
3) Confidence 0.03 Published 2007 Journal Journal of Clinical Biochemistry and Nutrition Section Body Doc Link PMC2127228 Disease Relevance 1.10 Pain Relevance 0.07

General Comments

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