INT50444

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Context Info
Confidence 0.39
First Reported 1995
Last Reported 2010
Negated 0
Speculated 1
Reported most in Body
Documents 11
Total Number 12
Disease Relevance 7.63
Pain Relevance 1.06

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

transport (Alb) enzyme binding (Alb) DNA binding (Alb)
protein complex (Alb) response to stress (Alb) cytoplasm (Alb)
Anatomy Link Frequency
Blood 2
sputum 2
eyes 2
lumen 2
eosinophil 2
Alb (Mus musculus)
Pain Link Frequency Relevance Heat
dexamethasone 5 97.44 Very High Very High Very High
lidocaine 1 91.28 High High
withdrawal 11 90.92 High High
anesthesia 5 86.24 High High
alcohol 5 79.60 Quite High
Inflammation 201 75.88 Quite High
cytokine 45 73.84 Quite High
isoflurane 5 70.28 Quite High
Spinal cord 14 69.56 Quite High
Sciatic nerve 12 68.92 Quite High
Disease Link Frequency Relevance Heat
Targeted Disruption 68 99.68 Very High Very High Very High
Pulmonary Disease 216 99.52 Very High Very High Very High
Proteinuria 21 99.16 Very High Very High Very High
Asthma 94 98.80 Very High Very High Very High
Diarrhoea 6 98.64 Very High Very High Very High
Confusion 4 98.18 Very High Very High Very High
Fever 1 97.70 Very High Very High Very High
Death 18 97.40 Very High Very High Very High
Hepatic Encephalopathy 46 97.30 Very High Very High Very High
Pressure And Volume Under Development 28 97.30 Very High Very High Very High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Serial sections, including anterior segment defects in the eyes of Alb-hßigh3 transgenic mice, were cut at 4 ?
Negative_regulation (defects) of Gene_expression (eyes) of Alb in eyes associated with targeted disruption
1) Confidence 0.39 Published 2007 Journal Molecular Vision Section Body Doc Link PMC2185514 Disease Relevance 0.25 Pain Relevance 0.09
Approximately 70% of differentiated embryonic stem (ES) cells express albumin and can be recovered by albumin promoter-based cell sorting.
Negative_regulation (recovered) of Gene_expression (express) of albumin in stem
2) Confidence 0.31 Published 2007 Journal Nat Protoc Section Abstract Doc Link 17406596 Disease Relevance 0 Pain Relevance 0.19
The therapeutic benefit of acidifying the gut lumen with synbiotics in cirrhotic patients with minimal HE was demonstrated by Liu et al. [123] who showed that synbiotic/probiotic supplementation ameliorates hepatic function as reflected by reduced bilirubin and albumin levels and prothrombin times [123].
Negative_regulation (reduced) of Gene_expression (levels) of albumin in lumen associated with cirrhosis and hepatic encephalopathy
3) Confidence 0.27 Published 2010 Journal Journal of Nutrition and Metabolism Section Body Doc Link PMC3017957 Disease Relevance 0.75 Pain Relevance 0.04
Blood levels of albumin and triglyceride were also decreased indicating that c-Met knockout mice could not regenerate liver mass and function efficiently (Figure S2C and D).


Negative_regulation (decreased) of Gene_expression (levels) of albumin in Blood associated with targeted disruption
4) Confidence 0.17 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2940888 Disease Relevance 0.42 Pain Relevance 0.17
Study-related toxicities were hypotension (6 patients); greater than 10% weight gain (6 patients); peripheral edema (9 patients); fever (4 patients); confusion (3 patients); diarrhea (3 patients); proteinuria, as identified by dipstick (3 patients), greater than 0.6 mg/dl decrease in serum albumin (11 patients); greater than 25% decrease in oncotic pressure (10 patients), and a decrease in ionized calcium (8 patients).
Negative_regulation (decrease) of Gene_expression (greater) of albumin associated with pressure and volume under development, diarrhoea, pressure volume 2 under development, proteinuria, fever, weight gain and confusion
5) Confidence 0.15 Published 1995 Journal Am. J. Clin. Oncol. Section Abstract Doc Link 7625372 Disease Relevance 1.47 Pain Relevance 0.07
The albumin concentration was determined colorimetrically at 628 nm based on albumin binding to bromcresol green, using an albumin BCG diagnostic kit (Sigma Chemical Co., St.
Spec (determined) Negative_regulation (determined) of Gene_expression (concentration) of albumin
6) Confidence 0.14 Published 2008 Journal Part Fibre Toxicol Section Body Doc Link PMC2546436 Disease Relevance 0.16 Pain Relevance 0.16
Free binding sites were blocked in 2% and 5% (w/v) bovine serum albumin (for nitrated proteins and LO, resp.) in 20?
Negative_regulation (blocked) of Gene_expression (resp.) of serum albumin
7) Confidence 0.08 Published 2010 Journal Mediators of Inflammation Section Body Doc Link PMC2852597 Disease Relevance 0 Pain Relevance 0.07
Four of these were albumin or albumin fractional products and the others were transferrin (TF), ?
Negative_regulation (were) of Gene_expression (products) of albumin
8) Confidence 0.05 Published 2010 Journal Journal of Biomedicine and Biotechnology Section Body Doc Link PMC2857808 Disease Relevance 0.96 Pain Relevance 0
Four of these were albumin or albumin fractional products and the others were transferrin (TF), ?
Negative_regulation (were) of Gene_expression (products) of albumin
9) Confidence 0.05 Published 2010 Journal Journal of Biomedicine and Biotechnology Section Body Doc Link PMC2857808 Disease Relevance 0.96 Pain Relevance 0
Using a blocking solution of 0.5% bovine serum albumin (BSA) in phosphate buffered saline (PBS), sections were incubated overnight at 4°C with either the selected scFv (10 ?
Negative_regulation (blocking) of Gene_expression (solution) of serum albumin
10) Confidence 0.05 Published 2010 Journal Arthritis and Rheumatism Section Body Doc Link PMC2905615 Disease Relevance 0.30 Pain Relevance 0.12
However, such treatment did reduce levels of albumin and eosinophil cationic protein in sputum samples obtained from patients with COPD (Grootendorst, Gauw, Benschop et al 2003).


Negative_regulation (reduce) of Gene_expression (levels) of albumin in sputum associated with pulmonary disease
11) Confidence 0.02 Published 2007 Journal International Journal of Chronic Obstructive Pulmonary Disease Section Body Doc Link PMC2699952 Disease Relevance 1.20 Pain Relevance 0.09
In patients with COPD, small but significant reductions in sputum levels of albumin and eosinophil cationic protein were observed.
Negative_regulation (reductions) of Gene_expression (levels) of albumin in eosinophil associated with pulmonary disease
12) Confidence 0.02 Published 2007 Journal International Journal of Chronic Obstructive Pulmonary Disease Section Body Doc Link PMC2699952 Disease Relevance 1.17 Pain Relevance 0.07

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