INT50508

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Context Info
Confidence 0.09
First Reported 1995
Last Reported 2006
Negated 0
Speculated 0
Reported most in Body
Documents 3
Total Number 3
Disease Relevance 1.32
Pain Relevance 0.26

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular region (FCER2) plasma membrane (FCER2)
Anatomy Link Frequency
granulocytes 1
FCER2 (Homo sapiens)
Pain Link Frequency Relevance Heat
Sciatica 2 91.92 High High
abdominal pain 1 90.32 High High
Inflammatory mediators 1 79.04 Quite High
cytokine 1 76.88 Quite High
Multiple sclerosis 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Hypersensitivity 21 99.16 Very High Very High Very High
Nerve Root Compression 2 91.92 High High
Anaphylaxis 1 90.96 High High
Abdominal Pain 1 90.32 High High
Pressure And Volume Under Development 1 89.68 High High
Contact Dermatitis 1 89.20 High High
Eczema 1 88.40 High High
Rhinitis 1 87.24 High High
Asthma 1 86.84 High High
INFLAMMATION 1 79.04 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
An immediate allergic response (type I hypersensitivity, as opposed to delayed-type, cell-mediated allergic reactions) includes the preferential synthesis and secretion of immunoglobulin E (IgE) molecules, which subsequently anchor efficiently to high-affinity receptors on tissue mast cells and basophilic granulocytes.
Localization (secretion) of immunoglobulin E in granulocytes associated with hypersensitivity
1) Confidence 0.09 Published 2006 Journal Nucleic Acids Research Section Body Doc Link PMC1540723 Disease Relevance 1.23 Pain Relevance 0.17
Immunoglobulin E antibodies to papaya proteinases and their relevance to chemonucleolysis.
Localization (relevance) of Immunoglobulin E
2) Confidence 0.07 Published 1995 Journal Spine Section Title Doc Link 7631245 Disease Relevance 0.09 Pain Relevance 0.09
Antibodies to glycyl endopeptidase were predominant in eight sera, and the mean amounts of immunoglobulin E directed against each protein were: glycyl endopeptidase, 4.21 IU/ml; caricain, 2.9 IU/ml; chymopapain, 1.97 IU/ml; and papain, 1.39 IU/ml.
Localization (directed) of immunoglobulin E
3) Confidence 0.07 Published 1995 Journal Spine Section Body Doc Link 7631245 Disease Relevance 0 Pain Relevance 0

General Comments

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