INT50548

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Context Info
Confidence 0.35
First Reported 1995
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 8
Total Number 8
Disease Relevance 2.64
Pain Relevance 0.43

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (ENOPH1) small molecule metabolic process (ENOPH1) nucleus (ENOPH1)
cellular nitrogen compound metabolic process (ENOPH1) cellular_component (ENOPH1) cytoplasm (ENOPH1)
Anatomy Link Frequency
urine 2
covering 1
ducts 1
ENOPH1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Inflammation 2 93.12 High High
Dismenorea 76 91.36 High High
Chronic pancreatitis 1 58.24 Quite High
Pain 9 5.00 Very Low Very Low Very Low
depression 8 5.00 Very Low Very Low Very Low
headache 5 5.00 Very Low Very Low Very Low
withdrawal 4 5.00 Very Low Very Low Very Low
Opioid 4 5.00 Very Low Very Low Very Low
gABA 2 5.00 Very Low Very Low Very Low
nud 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Togavirus Infection 139 99.68 Very High Very High Very High
Cv Unclassified Under Development 2 98.18 Very High Very High Very High
Pancreatitis 3 96.40 Very High Very High Very High
INFLAMMATION 2 93.12 High High
Necrosis 1 92.00 High High
Premenstrual Syndrome 134 91.76 High High
Sprains And Strains 22 90.32 High High
Mental Disorders 2 86.60 High High
Cicatrix 1 84.48 Quite High
Pancreatic Cancer 2 78.16 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In acute ischaemia, acinar cells which are dissociated from intercalated ducts lost their immunocytochemical reactivity for E1.
E1 Binding (reactivity) of in ducts associated with cv unclassified under development
1) Confidence 0.35 Published 1995 Journal Histochem. Cell Biol. Section Abstract Doc Link 7634150 Disease Relevance 1.05 Pain Relevance 0.15
As to clinical characteristics shown in Table 1, concentration of E1 and PdG in urine was elevated from the follicular to the late luteal phase in all three groups.
E1 Binding (concentration) of in urine
2) Confidence 0.09 Published 2007 Journal Biopsychosoc Med Section Body Doc Link PMC2253548 Disease Relevance 0.69 Pain Relevance 0.28
E1 and PdG were both indexed to creatinine (Cr) excretion in the same sample to control for variations in urine volume.
E1 Binding (creatinine) of in urine
3) Confidence 0.09 Published 2007 Journal Biopsychosoc Med Section Body Doc Link PMC2253548 Disease Relevance 0 Pain Relevance 0
However, as E1 and E2 envelope proteins exist as a heterodimer on the alphavirus surface, contribution of amino acid substitutions in the E2 protein to the observed differences between two antigens could not be underestimated and will be of future interest.
E1 Binding (heterodimer) of associated with togavirus infection
4) Confidence 0.08 Published 2010 Journal PLoS Neglected Tropical Diseases Section Body Doc Link PMC2907414 Disease Relevance 0.19 Pain Relevance 0
The E1-E2 heterodimers dissociate and E1 trimerizes, causing the E2 subunits to move away, permitting clustering of E1 to initiate fusion.
E1 Binding (dissociate) of
5) Confidence 0.08 Published 2010 Journal Virol J Section Body Doc Link PMC2831882 Disease Relevance 0.22 Pain Relevance 0
In alphaviruses, structural proteins E2 and E1 occur as a closely associated heterodimer on the surface of the virion, with E2 projecting outward and over E1, covering the E1 fusion loops [15,16].
E1 Binding (associated) of in covering
6) Confidence 0.07 Published 2010 Journal Virol J Section Body Doc Link PMC2831882 Disease Relevance 0.24 Pain Relevance 0
Eigenvectors E1 and E27 account for roughly 20% of the variance in the HI statistic.
E1 Binding (account) of
7) Confidence 0.04 Published 2005 Journal Int J Health Geogr Section Body Doc Link PMC1215506 Disease Relevance 0.05 Pain Relevance 0
Membrane strips were incubated with the purified hMAbs and hFabs as well as protein E1- and E2-specific mMAbs for 2 h at room temperature, followed by incubation with either AP-conjugated goat anti-human IgG F(ab?)
E1 Binding (incubated) of
8) Confidence 0.04 Published 2010 Journal PLoS Neglected Tropical Diseases Section Body Doc Link PMC2903468 Disease Relevance 0.20 Pain Relevance 0

General Comments

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