INT50585

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Context Info
Confidence 0.40
First Reported 1995
Last Reported 1995
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0
Pain Relevance 1.02

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Anatomy Link Frequency
striatum 1
Line (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Desipramine 4 99.98 Very High Very High Very High
Hippocampus 6 99.24 Very High Very High Very High
fluoxetine 4 97.90 Very High Very High Very High
antidepressant 5 91.40 High High
agonist 1 85.12 High High
antagonist 1 74.00 Quite High
Norepinephrine uptake inhibitor 1 71.68 Quite High
Serotonin 1 61.48 Quite High

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Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Repeated treatment with fluoxetine increased base-line levels of 5-HT in the striatum and hippocampus; repeated treatment with desipramine increased base-line 5-HT levels in the striatum only, and repeated treatment with mianserin did not alter base-line 5-HT levels.
Positive_regulation (increased) of base-line in striatum associated with desipramine, hippocampus and fluoxetine
1) Confidence 0.40 Published 1995 Journal J. Pharmacol. Exp. Ther. Section Abstract Doc Link 7636750 Disease Relevance 0 Pain Relevance 1.02

General Comments

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