INT50587

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Context Info
Confidence 0.44
First Reported 1995
Last Reported 1995
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0
Pain Relevance 0.52

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (Htr1a) signal transducer activity (Htr1a)
Htr1a (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Serotonin 1 99.68 Very High Very High Very High
antidepressant 5 96.64 Very High Very High Very High
fluoxetine 4 94.32 High High
Norepinephrine uptake inhibitor 1 93.28 High High
Desipramine 4 92.00 High High
antagonist 1 90.12 High High
Hippocampus 6 69.52 Quite High
agonist 1 25.00 Low Low

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Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Extracellular levels of serotonin (5-HT) and the regulation of 5-HT release by the 5-HT1A receptor were examined after single and repeated treatment with different types of antidepressant drugs: the selective 5-HT uptake inhibitor fluoxetine, the selective norepinephrine uptake inhibitor desipramine and the 5-HT2A/2C/alpha 2 receptor antagonist mianserin (each at 15.0 mg/kg).
Regulation (regulation) of Localization (release) of 5-HT1A associated with desipramine, norepinephrine uptake inhibitor, antidepressant, antagonist, serotonin and fluoxetine
1) Confidence 0.44 Published 1995 Journal J. Pharmacol. Exp. Ther. Section Abstract Doc Link 7636750 Disease Relevance 0 Pain Relevance 0.52

General Comments

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