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Context Info
Confidence 0.43
First Reported 1995
Last Reported 1995
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0
Pain Relevance 0.37

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oxidoreductase activity (Dio1) endoplasmic reticulum (Dio1) nucleus (Fos)
DNA binding (Fos) transcription factor binding (Fos)
Dio1 (Mus musculus)
Fos (Mus musculus)
Pain Link Frequency Relevance Heat
agonist 5 96.68 Very High Very High Very High
Dopamine 5 80.88 Quite High
Opioid 1 68.80 Quite High


Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
During a transient postnatal period, c-fos expression in a patchy distribution was induced by D1 receptor activation: only a faint response was detected on postnatal day 1, but islands of strong hybridization signals for c-fos mRNA in response to the D1 agonist were observed at postnatal day 3, with a progressive decrease in intensity from day 6 to day 15.
Positive_regulation (activation) of D1 Positive_regulation (induced) of Gene_expression (expression) of c-fos associated with agonist
1) Confidence 0.43 Published 1995 Journal Brain Res. Mol. Brain Res. Section Abstract Doc Link 7637573 Disease Relevance 0 Pain Relevance 0.37

General Comments

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