INT50634

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Context Info
Confidence 0.02
First Reported 1995
Last Reported 1995
Negated 0
Speculated 0
Reported most in Title
Documents 1
Total Number 2
Disease Relevance 0
Pain Relevance 0.65

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lyase activity (Ddc, Glul) intracellular (Ddc, Glul) cytoplasm (Ddc, Glul)
mitochondrion (Glul) Golgi apparatus (Glul) protein complex (Glul)
Anatomy Link Frequency
striatum 2
Ddc (Rattus norvegicus)
Glul (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Glutamate 12 100.00 Very High Very High Very High
Enkephalin 4 99.84 Very High Very High Very High
substance P 2 78.08 Quite High

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Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The effect of L-DOPA on the gene expression of preproenkephalin and glutamate decarboxylase (M(r) 67,000) differs from the increase in striatal enkephalin content and glutamate decarboxylase activity previously found following L-DOPA treatment.
L-DOPA Regulation (effect) of Gene_expression (expression) of glutamate decarboxylase associated with glutamate and enkephalin
1) Confidence 0.02 Published 1995 Journal Neuroscience Section Abstract Doc Link 7637869 Disease Relevance 0 Pain Relevance 0.38
Chronic L-DOPA treatment differentially regulates gene expression of glutamate decarboxylase, preproenkephalin and preprotachykinin in the striatum of 6-hydroxydopamine-lesioned rat.
L-DOPA Regulation (regulates) of Gene_expression (expression) of glutamate decarboxylase in striatum associated with glutamate and enkephalin
2) Confidence 0.01 Published 1995 Journal Neuroscience Section Title Doc Link 7637869 Disease Relevance 0 Pain Relevance 0.26

General Comments

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