INT50711

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Context Info
Confidence 0.01
First Reported 1995
Last Reported 1999
Negated 0
Speculated 1
Reported most in Abstract
Documents 2
Total Number 2
Disease Relevance 0
Pain Relevance 0.39

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

mitochondrion (Comt) plasma membrane (Comt) cytoplasm (Comt)
Anatomy Link Frequency
plasma 2
chromaffin cells 2
Comt (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Catecholamine 2 100.00 Very High Very High Very High
Clonidine 6 94.40 High High
medulla 2 70.24 Quite High
agonist 1 50.96 Quite High
Nicotine 3 25.00 Low Low
Enkephalin 1 25.00 Low Low
Neurotransmitter 1 25.00 Low Low
antagonist 1 25.00 Low Low
Calcium channel 1 25.00 Low Low

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Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
As adrenal medullary chromaffin cells express imidazoline binding sites in the absence of alpha 2-adrenergic receptors, these cells provide an ideal system in which to determine whether imidazolines can influence catecholamine gene expression through nonadrenergic receptors.
Regulation (influence) of Gene_expression (expression) of catecholamine gene in chromaffin cells associated with catecholamine
1) Confidence 0.01 Published 1995 Journal J. Neurochem. Section Abstract Doc Link 7643129 Disease Relevance 0 Pain Relevance 0.34
This study examined the impact of a chronic physiological elevation of plasma cortisol levels on adrenal catecholamine synthetic enzyme and proenkephalin A mRNA expression in foetal sheep.
Spec (examined) Regulation (impact) of Gene_expression (expression) of catecholamine synthetic enzyme in plasma associated with catecholamine
2) Confidence 0.00 Published 1999 Journal J. Neuroendocrinol. Section Abstract Doc Link 10444314 Disease Relevance 0 Pain Relevance 0.05

General Comments

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