INT50848

Context Info Confidence 0.38 First Reported 1995 Last Reported 2010 Negated 0 Speculated 0 Reported most in Body Documents 5 Total Number 5 Disease Relevance 2.45 Pain Relevance 0.35

nucleolus (ZFP91) nucleus (ZFP91) intracellular (ZFP91) ligase activity (ZFP91)

Anatomy Link Frequency internal 1 body 1 ZFP91 (Homo sapiens)

Pain Link Frequency Relevance Heat addiction 163 97.76 Pain 4 81.52 withdrawal 63 72.04 methadone 1 50.00 depression 3 40.64 rheumatoid arthritis 1 14.96 tolerance 5 8.56 Nicotine 62 5.00 imagery 3 5.00 antidepressant 2 5.00

Disease Link Frequency Relevance Heat Mental Disorders 134 100.00 Asperger Syndrome 99 99.44 Psychotic Affective Disorders 1 98.72 Psychosis 11 97.68 Schizophrenia 1 96.60 Syndrome 8 89.76 Disease 47 89.16 Rigor 1 73.60 Autism 25 73.32 Attention Deficit Hyperactivity Disorder 9 69.20

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

What large body of peer reviewed data established the validity of the DSM criteria?

Regulation (validity) of DSM in body

1) Confidence 0.38 Published 2010 Journal Harm Reduct J Section Body Doc Link PMC2992487 Disease Relevance 0.42 Pain Relevance 0.27

Alas, as Sadler noted, "The introduction to DSM IV is really excellent.

Regulation (introduction) of DSM

2) Confidence 0.29 Published 2008 Journal Child Adolesc Psychiatry Ment Health Section Body Doc Link PMC2275214 Disease Relevance 0.99 Pain Relevance 0

CONCLUSIONS: The change in DSM-III-R from DSM-III childhood criteria appears to have resulted in a decrease in internal consistency and rates of antisocial personality disorder for women, but not for men.

Regulation (change) of DSM-III-R in internal

3) Confidence 0.03 Published 1995 Journal Am J Psychiatry Section Body Doc Link 7653686 Disease Relevance 0.06 Pain Relevance 0

A connection between mental disorder and freedom is clearly present in the introduction of the fourth edition to the Diagnostic and Statistical Manual of Mental Disorders (DSM-IV).

Regulation (introduction) of DSM-IV associated with mental disorders

4) Confidence 0.03 Published 2010 Journal Theor Med Bioeth Section Body Doc Link PMC2975916 Disease Relevance 0.48 Pain Relevance 0.08

Using several such instruments and including only individuals who fulfilled both ICD-10 and DSM-I0 criteria for AS, as was the case in this study should improve the detection rate of the features typical for AS.

Regulation (fulfilled) of DSM-I0 associated with asperger syndrome

5) Confidence 0.02 Published 2005 Journal BMC Psychiatry Section Body Doc Link PMC1097741 Disease Relevance 0.50 Pain Relevance 0

General Comments

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