INT50855

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Context Info
Confidence 0.65
First Reported 1994
Last Reported 2007
Negated 1
Speculated 0
Reported most in Body
Documents 4
Total Number 4
Disease Relevance 3.07
Pain Relevance 0.71

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleolus (TRIM21) RNA binding (TRIM21) nucleus (TRIM21)
intracellular (TRIM21) DNA binding (TRIM21) ligase activity (TRIM21)
TRIM21 (Homo sapiens)
Pain Link Frequency Relevance Heat
Migraine 2 98.88 Very High Very High Very High
fibrosis 1 98.48 Very High Very High Very High
Arthritis 1 96.64 Very High Very High Very High
intrathecal 2 96.32 Very High Very High Very High
imagery 5 93.68 High High
Spinal cord 1 91.36 High High
Central nervous system 4 89.36 High High
Pain 2 64.96 Quite High
Multiple sclerosis 1 37.04 Quite Low
palliative 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Headache 2 98.88 Very High Very High Very High
Pulmonary Fibrosis 1 98.48 Very High Very High Very High
Dilated Cardiomyopathy 4 98.08 Very High Very High Very High
Generalized Anxiety Disorder 5 97.74 Very High Very High Very High
Cv General 2 Under Development 3 96.76 Very High Very High Very High
Arthritis 1 96.64 Very High Very High Very High
Disease 10 96.24 Very High Very High Very High
Arthralgia 2 95.60 Very High Very High Very High
Dry Eye 1 94.88 High High
Pharyngitis 1 92.56 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Antinuclear antibodies were positive in 42.5% and anti-SS-A (Ro) in 20%.
Gene_expression (positive) of SS-A
1) Confidence 0.65 Published 1995 Journal Ann Med Interne (Paris) Section Abstract Doc Link 7653943 Disease Relevance 0.91 Pain Relevance 0.56
Positive antinuclear antibodies and or rheumatoid factors were discovered in 38% of patients although the anti-SSA antibody was found in only one patient and anti-SSB in none.
Gene_expression (found) of SSA
2) Confidence 0.65 Published 1994 Journal Semin. Arthritis Rheum. Section Abstract Doc Link 7801139 Disease Relevance 0.99 Pain Relevance 0.06
Two of them were anti-Ro/SS-A positive (both with isolated complete AV block).
Gene_expression (positive) of SS-A
3) Confidence 0.65 Published 2007 Journal Cardiovasc Ultrasound Section Body Doc Link PMC1845152 Disease Relevance 0.45 Pain Relevance 0
Anti-GAD, anti-gliadin, anti-endomysial and anti-transglutaminase antibodies and paraneoplastic autoantibodies (anti-Hu, -Ro and Ri) were not detected in serum.
Neg (not) Gene_expression (detected) of -Ro associated with generalized anxiety disorder
4) Confidence 0.58 Published 2006 Journal BMC Neurol Section Body Doc Link PMC1351204 Disease Relevance 0.72 Pain Relevance 0.09

General Comments

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