INT50989

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Context Info
Confidence 0.42
First Reported 1995
Last Reported 2002
Negated 0
Speculated 1
Reported most in Abstract
Documents 2
Total Number 2
Disease Relevance 0.86
Pain Relevance 1.02

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Il1b) aging (Il1b) extracellular region (Il1b)
Anatomy Link Frequency
hypothalamus 2
Il1b (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Morphine 7 100.00 Very High Very High Very High
cocaine 6 100.00 Very High Very High Very High
intrathecal 3 100.00 Very High Very High Very High
Inflammation 6 98.76 Very High Very High Very High
withdrawal 1 80.64 Quite High
Antinociceptive 2 50.96 Quite High
narcan 2 42.80 Quite Low
Opioid 1 26.00 Quite Low
Pain 1 25.00 Low Low
Disease Link Frequency Relevance Heat
Nociception 3 99.80 Very High Very High Very High
INFLAMMATION 5 98.76 Very High Very High Very High
Disease 1 74.44 Quite High
Injury 1 73.96 Quite High
Stress 1 73.64 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The present study was to investigate the effect of intrathecal (i.t.) injection of interleukin-1 beta (IL-1 beta) on nociception in normal and inflammatory rats.
Spec (investigate) Regulation (effect) of Spec (investigate) Positive_regulation (injection) of IL-1 beta associated with nociception, inflammation and intrathecal
1) Confidence 0.42 Published 2002 Journal Cytokine Section Abstract Doc Link 12200111 Disease Relevance 0.64 Pain Relevance 0.38
In this study, we compared the effects of morphine, ethanol and cocaine on IL-1 beta induction of FOS-IR in the rat hypothalamus.
Regulation (effects) of Positive_regulation (induction) of IL-1 beta in hypothalamus associated with cocaine and morphine
2) Confidence 0.24 Published 1995 Journal Adv. Exp. Med. Biol. Section Abstract Doc Link 7668153 Disease Relevance 0.22 Pain Relevance 0.64

General Comments

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