INT50992

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Context Info
Confidence 0.26
First Reported 1995
Last Reported 2002
Negated 2
Speculated 0
Reported most in Abstract
Documents 2
Total Number 2
Disease Relevance 0.73
Pain Relevance 2.22

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

aging (Fos) nucleolus (Fos) nucleus (Fos)
DNA binding (Fos) transcription factor binding (Fos) response to stress (Fos)
Anatomy Link Frequency
CPU 2
Fos (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Morphine 14 99.98 Very High Very High Very High
cocaine 6 99.82 Very High Very High Very High
medulla 2 94.56 High High
Snapping jaw 5 90.16 High High
anesthesia 1 87.24 High High
Spinal cord 1 84.20 Quite High
Pain 1 75.12 Quite High
Face pain 1 73.68 Quite High
Opioid 1 68.80 Quite High
nociceptor 1 25.00 Low Low
Disease Link Frequency Relevance Heat
Injury 5 90.44 High High
Temporomandibular Joint Syndrome 5 90.16 High High
Pain 1 75.12 Quite High
Disease 1 47.00 Quite Low
Stress 1 46.20 Quite Low
Facial Pain 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Morphine inhibition of Fos-LI produced in laminae I-II at the Vc/C2 junction region was diminished in vagotomized males compared to intact animals, but not affected in females.
Neg (not) Regulation (affected) of Negative_regulation (inhibition) of Fos associated with morphine
1) Confidence 0.26 Published 2002 Journal Pain Section Abstract Doc Link 11932076 Disease Relevance 0.73 Pain Relevance 1.39
By contrast, chronic cocaine did not affect FOS responsiveness to IL-1 beta in the PVN even though the treatment was able to desensitize the FOS responsiveness to acute cocaine in the CPU, nAcc, and LC.
Neg (not) Regulation (affect) of Negative_regulation (responsiveness) of FOS in CPU associated with cocaine
2) Confidence 0.23 Published 1995 Journal Adv. Exp. Med. Biol. Section Abstract Doc Link 7668153 Disease Relevance 0 Pain Relevance 0.83

General Comments

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