INT51148

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Context Info
Confidence 0.34
First Reported 1993
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 6
Total Number 6
Disease Relevance 2.42
Pain Relevance 0.42

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell adhesion (CDH16) plasma membrane (CDH16)
Anatomy Link Frequency
muscle tissue 1
neural 1
glands 1
CDH16 (Homo sapiens)
Pain Link Frequency Relevance Heat
endometriosis 1 96.96 Very High Very High Very High
Dismenorea 5 82.96 Quite High
metalloproteinase 24 5.00 Very Low Very Low Very Low
Kinase C 14 5.00 Very Low Very Low Very Low
cva 10 5.00 Very Low Very Low Very Low
cytokine 7 5.00 Very Low Very Low Very Low
headache 6 5.00 Very Low Very Low Very Low
agonist 5 5.00 Very Low Very Low Very Low
corticosteroid 2 5.00 Very Low Very Low Very Low
Inflammation 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Adhesions 95 99.64 Very High Very High Very High
Cancer 42 99.44 Very High Very High Very High
Prostate Cancer 87 99.32 Very High Very High Very High
Muscular Dystrophy 70 97.88 Very High Very High Very High
Endometriosis (extended) 2 96.96 Very High Very High Very High
Meningioma 6 87.92 High High
Dysmenorrhea 5 82.96 Quite High
Metastasis 33 77.68 Quite High
Disease 31 63.72 Quite High
Disease Progression 8 22.16 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The higher receptor expression in invading glands is specific because the invading and noninvading stroma showed similar receptor expression, invading and noninvading glands showed similar expression of cadherin, a cell adhesion receptor, and ectopic and eutopic endometrial glands from endometriosis showed similar hCG/LH receptor expression.
Gene_expression (expression) of cadherin in glands associated with endometriosis and adhesions
1) Confidence 0.34 Published 1993 Journal J. Clin. Endocrinol. Metab. Section Abstract Doc Link 7680356 Disease Relevance 0.64 Pain Relevance 0.42
RT-PCR analysis revealed the expression of M-cadherin, Myf-5, Myogenin, Pax7, MyoD and MRF4 in normal and DMD CD133+CXCR4+CD34- cells after 7 days of co-culture.
Gene_expression (expression) of M-cadherin associated with muscular dystrophy
2) Confidence 0.10 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2377332 Disease Relevance 0.25 Pain Relevance 0
Multiple studies have also demonstrated changes in expression of ECM molecules in advanced PCa tumor samples, such as increased expression of BSP and Cadherin 11 [36,37], or decreased coll VII expression [38].
Gene_expression (expression) of Cadherin associated with cancer and prostate cancer
3) Confidence 0.04 Published 2004 Journal Reprod Biol Endocrinol Section Body Doc Link PMC320496 Disease Relevance 0.98 Pain Relevance 0
Several types have been described, including N-cadherin in neural and muscle tissue, P-cadherin in placental tissue, E-cadherin found in epithelial cells, and VE-cadherin expressed exclusively in endothelial cells [47,48].
Gene_expression (expressed) of P-cadherin in neural
4) Confidence 0.03 Published 2005 Journal Cerebrospinal Fluid Res Section Body Doc Link PMC1285366 Disease Relevance 0.28 Pain Relevance 0
However, a recent comprehensive set of studies unequivocally demonstrated that the desmosomal components desmoglein 2 (Dsg 2), desmocollin 2 (Dsc 2), desmoplakin and plakophilin-2 as well as the adherens junction components N-cadherin, cadherin-11, ?
Gene_expression (components) of cadherin
5) Confidence 0.01 Published 2008 Journal Histochem Cell Biol Section Body Doc Link PMC2413110 Disease Relevance 0 Pain Relevance 0
Several types have been described, including N-cadherin in neural and muscle tissue, P-cadherin in placental tissue, E-cadherin found in epithelial cells, and VE-cadherin expressed exclusively in endothelial cells [47,48].
Gene_expression (expressed) of P-cadherin in muscle tissue
6) Confidence 0.01 Published 2005 Journal Cerebrospinal Fluid Res Section Body Doc Link PMC1285366 Disease Relevance 0.28 Pain Relevance 0

General Comments

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