INT51336

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Context Info
Confidence 0.12
First Reported 1993
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 3
Total Number 4
Disease Relevance 1.50
Pain Relevance 0.66

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Vtn) extracellular region (Vtn) cell adhesion (Vtn)
proteinaceous extracellular matrix (Vtn) extracellular matrix organization (Vtn)
Vtn (Mus musculus)
Pain Link Frequency Relevance Heat
Opioid 1 99.24 Very High Very High Very High
antagonist 14 87.48 High High
Spinal cord 66 84.88 Quite High
Demyelination 246 80.84 Quite High
Central nervous system 70 74.84 Quite High
Inflammation 86 72.32 Quite High
Peripheral nerve injury 1 34.04 Quite Low
Hyperalgesia 1 32.64 Quite Low
Multiple sclerosis 47 5.00 Very Low Very Low Very Low
Neuritis 34 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cancer 82 88.96 High High
Cardiovascular Disease 1 88.52 High High
Sprains And Strains 166 88.24 High High
Demyelinating Disease 461 80.84 Quite High
Viral Meningitis 28 73.40 Quite High
INFLAMMATION 86 72.84 Quite High
Apoptosis 14 62.36 Quite High
Contagious Ecthyma 2 59.44 Quite High
Nervous System Injury 1 34.04 Quite Low
Hyperalgesia 1 32.64 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
A cyclic pentapeptide called EMD66203 [cyclic L-Arg-L-Gly-L-Asp-D-Phe-L-Val (RGDfV) peptide or cyclo(-Arg-GlyAsp-D-Phe-Val)](Aumailley et al. 1991) was shown preferential inhibition of vitronectin binding to the ?
vitronectin Binding (binding) of
1) Confidence 0.12 Published 2008 Journal Perspectives in Medicinal Chemistry Section Body Doc Link PMC2746574 Disease Relevance 0.57 Pain Relevance 0.11
As alteration of the MHV S protein influences pathogenesis, it is important to understand how alteration of the S protein alters the virus-host interaction.
S protein Binding (alteration) of
2) Confidence 0.05 Published 2010 Journal Interdisciplinary Perspectives on Infectious Diseases Section Body Doc Link PMC2905936 Disease Relevance 0.43 Pain Relevance 0.22
As alteration of the MHV S protein influences pathogenesis, it is important to understand how alteration of the S protein alters the virus-host interaction.
S protein Binding (alteration) of
3) Confidence 0.04 Published 2010 Journal Interdisciplinary Perspectives on Infectious Diseases Section Body Doc Link PMC2905936 Disease Relevance 0.50 Pain Relevance 0.23
SP-40,40 bound to beta-endorphin via C-terminal non-opioid portion of beta-endorphin as well as S-protein (vitronectin) bound.
S-protein Binding (bound) of associated with opioid
4) Confidence 0.03 Published 1993 Journal Biol. Pharm. Bull. Section Abstract Doc Link 7689889 Disease Relevance 0 Pain Relevance 0.10

General Comments

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