INT51341

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Context Info
Confidence 0.14
First Reported 1993
Last Reported 1993
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 4
Disease Relevance 0
Pain Relevance 0.38

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoplasm (Pomc, Clu) extracellular space (Pomc, Clu) extracellular region (Pomc, Clu)
mitochondrion (Clu) endoplasmic reticulum (Clu) response to stress (Clu)
Anatomy Link Frequency
brain 1
band 1
Pomc (Rattus norvegicus)
Clu (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Opioid 4 99.20 Very High Very High Very High

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Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Beta-endorphin bound mainly to SP-40,40, but not to S-protein, in the soluble membrane attack complex (SMAC, SC5b-9) of complement, because the results of autoradiography of the cross-linking experiment of SMAC with [125I] beta-endorphin revealed only a typical band of SP-40,40.
Beta-endorphin Binding (bound) of SP-40 in band
1) Confidence 0.14 Published 1993 Journal Biol. Pharm. Bull. Section Abstract Doc Link 7689889 Disease Relevance 0 Pain Relevance 0.10
Beta-endorphin binding activity of SP-40,40.
Beta-endorphin Binding (activity) of SP-40
2) Confidence 0.14 Published 1993 Journal Biol. Pharm. Bull. Section Title Doc Link 7689889 Disease Relevance 0 Pain Relevance 0.10
The binding of SP-40,40 to beta-endorphin inhibited the binding of beta-endorphin to its receptor of rat brain; thus SP-40,40 might inhibit the biological action of beta-endorphin.
beta-endorphin Binding (binding) of SP-40 in brain
3) Confidence 0.14 Published 1993 Journal Biol. Pharm. Bull. Section Abstract Doc Link 7689889 Disease Relevance 0 Pain Relevance 0.09
SP-40,40 bound to beta-endorphin via C-terminal non-opioid portion of beta-endorphin as well as S-protein (vitronectin) bound.
beta-endorphin Binding (bound) of SP-40 associated with opioid
4) Confidence 0.12 Published 1993 Journal Biol. Pharm. Bull. Section Abstract Doc Link 7689889 Disease Relevance 0 Pain Relevance 0.10

General Comments

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