INT5137

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Context Info
Confidence 0.47
First Reported 1984
Last Reported 2010
Negated 4
Speculated 1
Reported most in Abstract
Documents 45
Total Number 47
Disease Relevance 16.91
Pain Relevance 18.47

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Anatomy Link Frequency
stroma 1
superior 1
brain 1
uterine 1
PCA 1
PCa (Homo sapiens)
Pain Link Frequency Relevance Heat
Patient controlled alalgesia 133 100.00 Very High Very High Very High
alcohol 89 100.00 Very High Very High Very High
analgesia 37 100.00 Very High Very High Very High
Morphine 31 100.00 Very High Very High Very High
sodium channel 164 99.98 Very High Very High Very High
Chronic pancreatitis 29 99.82 Very High Very High Very High
Perioperative pain 25 99.82 Very High Very High Very High
opiate 2 99.80 Very High Very High Very High
depression 26 99.78 Very High Very High Very High
Nerve growth factor 12 98.72 Very High Very High Very High
Disease Link Frequency Relevance Heat
Prostate Cancer 219 100.00 Very High Very High Very High
Reprotox - General 1 195 100.00 Very High Very High Very High
Pancreatic Cancer 114 100.00 Very High Very High Very High
Vascular Disease 4 100.00 Very High Very High Very High
Hyperammonemia 3 99.98 Very High Very High Very High
Cystadenoma 21 99.90 Very High Very High Very High
Pancreatitis 37 99.82 Very High Very High Very High
Post Operative Pain 25 99.82 Very High Very High Very High
Depression 25 99.78 Very High Very High Very High
Adenocarcinoma 4 99.72 Very High Very High Very High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
CONCLUSION: association of magnesium to morphin PCA does not help to reduce morphin consumption, and does not affect the control of the stress reaction in major digestive surgery.


PCA Binding (association) of
1) Confidence 0.47 Published 2010 Journal Tunis Med Section Body Doc Link 20517827 Disease Relevance 0 Pain Relevance 0
Electrical stimulation of the superior laryngeal nerve caused depression of AN and PCA activity, and hence does not reproduce the effects of negative pressure.
PCA Binding (activity) of in PCA associated with depression
2) Confidence 0.37 Published 1984 Journal J Appl Physiol Section Abstract Doc Link 6706780 Disease Relevance 0.10 Pain Relevance 0.23
These facts impart biological plausibility to our findings on the association between PCa and ADT with osteoporosis and fractures as shown by the forests plots (Figure 3A, 3B and 4).
PCa Binding (association) of associated with osteoporosis and prostate cancer
3) Confidence 0.35 Published 2010 Journal BMC Urol Section Body Doc Link PMC2882358 Disease Relevance 1.09 Pain Relevance 0
Of the two studies that analyzed patients with PCa not under ADT and healthy controls, neither found an association between PCa and an increased risk of osteoporosis.
PCa Neg (neither) Binding (association) of associated with osteoporosis and prostate cancer
4) Confidence 0.35 Published 2010 Journal BMC Urol Section Body Doc Link PMC2882358 Disease Relevance 1.47 Pain Relevance 0
For the majority of items on the patient EOC questionnaire, trends suggest that greater percentages of patients reported the most positive response for fentanyl ITS than they did for morphine IV PCA in both studies; differences were particularly noteworthy for items on the Movement subscale.
PCA Binding (did) of associated with morphine
5) Confidence 0.31 Published 2009 Journal Pain Manag Nurs Section Abstract Doc Link 19706349 Disease Relevance 0.23 Pain Relevance 0.99
METHODS: Fifty patients undergoing hallux valgus repair were randomly allocated to receive an infusion of 0.125% levobupivacaine administered through a popliteal catheter as an automated regular bolus (n = 25) or as a continuous infusion (n = 25), both combined with PCA.
PCA Binding (combined) of
6) Confidence 0.31 Published 2009 Journal Anesthesiology Section Body Doc Link 19104182 Disease Relevance 0 Pain Relevance 0
The results of the study comparing the pharmacokinetics of fentanyl ITS with fentanyl IV PCA (80 ?
PCA Binding (comparing) of associated with patient controlled alalgesia
7) Confidence 0.31 Published 2007 Journal Therapeutics and Clinical Risk Management Section Body Doc Link PMC1936285 Disease Relevance 0.05 Pain Relevance 0.41
Of these, 9,571 (1%) were associated with PCA.
PCA Binding (associated) of
8) Confidence 0.31 Published 2008 Journal Am J Health Syst Pharm Section Body Doc Link 18281735 Disease Relevance 0 Pain Relevance 0
There were 624 records of PCA associated with harm, corresponding to 6.5% of the patients.
PCA Binding (associated) of
9) Confidence 0.31 Published 2008 Journal Am J Health Syst Pharm Section Body Doc Link 18281735 Disease Relevance 0 Pain Relevance 0
The PCA was applied to the 145 patients with no missing data for the 27 items included in the analysis.
PCA Binding (applied) of
10) Confidence 0.31 Published 2010 Journal BMC Ophthalmol Section Body Doc Link PMC2832632 Disease Relevance 0 Pain Relevance 0
PURPOSE: To identify the factors that threaten patient safety when using patient-controlled analgesia (PCA) and to obtain an evidence-based estimate of the probability of death from user programming errors associated with PCA.
PCA Binding (associated) of associated with patient controlled alalgesia and death
11) Confidence 0.31 Published 2003 Journal Can J Anaesth Section Abstract Doc Link 12670807 Disease Relevance 0.17 Pain Relevance 0.37
OBJECTIVES: The objective of the study is to evaluate the safety and efficacy of an opioid drug (fentanil) administered by PCA associated with a sedative-adjuvant drug (midazolam) administered by continuous infusion in children having undergone major neurosurgical procedures.
PCA Binding (associated) of
12) Confidence 0.30 Published 2008 Journal Childs Nerv Syst Section Body Doc Link 17639417 Disease Relevance 0 Pain Relevance 0
Thirteen extra tasks were identified by the Clinical Trial panel to be associated only with IV PCA, and these eliminated steps primarily explained the estimated total nursing time difference between IV PCA and fentanyl ITS.
PCA Binding (associated) of
13) Confidence 0.30 Published 2007 Journal Pain Manag Nurs Section Abstract Doc Link 17544128 Disease Relevance 0.07 Pain Relevance 0.25
Nevertheless, the control gained by self-administration, uniformity of analgesia, and low level of adverse results associated with PCA provides higher patient satisfaction and decreased sedation when compared with traditional intramuscular dosing.
PCA Binding (associated) of associated with patient controlled alalgesia, sleep disorders and analgesia
14) Confidence 0.30 Published 1991 Journal The Yale Journal of Biology and Medicine Section Abstract Doc Link PMC2589526 Disease Relevance 0.92 Pain Relevance 2.24
Despite the extensive use of this analgesic technique, there are not large population studies to determine the frequency or types of complications associated with PCA in the literature.
PCA Binding (associated) of associated with analgesic and patient controlled alalgesia
15) Confidence 0.30 Published 1992 Journal J Pain Symptom Manage Section Abstract Doc Link 1287108 Disease Relevance 0.09 Pain Relevance 0.92
CONCLUSION: No confounding variables explained the significant association between PCA pump use and in-hospital surgical site infection.
PCA Neg (No) Binding (association) of
16) Confidence 0.30 Published 2002 Journal Surg Infect (Larchmt) Section Body Doc Link 12519477 Disease Relevance 0 Pain Relevance 0
PCA is apparently associated with a vascular narrowing causing cerebral ischemia with increased diffusion.
PCA Binding (associated) of associated with cv general 4 under development, vascular disease and ischemia
17) Confidence 0.30 Published 2002 Journal Neurol. Res. Section Abstract Doc Link 12238622 Disease Relevance 0.58 Pain Relevance 0.34
These complications were attributable to overdosage (escalating dosage to meet patient analgesic needs or someone other than the patient administering drug through the PCA device) or to interaction of PCA drugs with concurrent medications.
PCA Binding (interaction) of associated with analgesic and patient controlled alalgesia
18) Confidence 0.30 Published 1992 Journal J Pain Symptom Manage Section Abstract Doc Link 1287108 Disease Relevance 0.08 Pain Relevance 1.03
Our objectives were to determine if a PCA recording document (monitoring form) could be used to identify potential problems associated with PCA therapy and to identify measures that could be taken to improve analgesic therapy with this method of administration.
PCA Binding (associated) of associated with analgesic and patient controlled alalgesia
19) Confidence 0.30 Published 1991 Journal DICP Section Abstract Doc Link 1803789 Disease Relevance 0 Pain Relevance 0.87
The hypothesis related to the superiority of PCA was accepted, while the association between PCA and increased vital capacity was not supported.
PCA Binding (association) of associated with patient controlled alalgesia
20) Confidence 0.30 Published 1991 Journal J Perinatol Section Abstract Doc Link 1890479 Disease Relevance 0.38 Pain Relevance 1.37

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