INT5148

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.44
First Reported 1992
Last Reported 2010
Negated 2
Speculated 3
Reported most in Body
Documents 25
Total Number 28
Disease Relevance 21.58
Pain Relevance 4.05

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (CD40LG) extracellular region (CD40LG) plasma membrane (CD40LG)
Anatomy Link Frequency
blood 3
body 2
eye 1
juvenile 1
B lymphocytes 1
CD40LG (Homo sapiens)
Pain Link Frequency Relevance Heat
Neuritis 2 99.96 Very High Very High Very High
Multiple sclerosis 6 98.68 Very High Very High Very High
spinal inflammation 15 98.56 Very High Very High Very High
imagery 48 98.24 Very High Very High Very High
nud 4 97.84 Very High Very High Very High
peptic ulcer disease 2 97.72 Very High Very High Very High
rheumatoid arthritis 180 97.64 Very High Very High Very High
cytokine 95 97.16 Very High Very High Very High
adenocard 12 96.08 Very High Very High Very High
Arthritis 177 93.40 High High
Disease Link Frequency Relevance Heat
Adhesions 17 100.00 Very High Very High Very High
Ulcers 7 100.00 Very High Very High Very High
Neuritis 1 99.96 Very High Very High Very High
Herpes Zoster 18 99.66 Very High Very High Very High
Stress 20 99.64 Very High Very High Very High
Cytomegalovirus Infection 35 99.60 Very High Very High Very High
Diabetes Mellitus 66 99.48 Very High Very High Very High
Insulin Resistance 14 99.04 Very High Very High Very High
Cancer 116 99.00 Very High Very High Very High
Lymphatic System Cancer 73 98.84 Very High Very High Very High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
At the same time, blood was drawn for the determination of the erythrocyte sedimentation rate (Westergren method), C-reactive protein, and IgM rheumatoid factor by standard laboratory methods.
Spec (determination) Regulation (determination) of IgM in blood
1) Confidence 0.44 Published 2005 Journal Arthritis Res Ther Section Body Doc Link PMC1175028 Disease Relevance 1.10 Pain Relevance 0.53
The influence of Helicobacter pylori eradication on leptin, soluble CD40 ligand, oxidative stress and body composition in patients with peptic ulcer disease.
Regulation (influence) of CD40 ligand in body associated with stress, peptic ulcer disease, ulcers and disease
2) Confidence 0.44 Published 2009 Journal Intern. Med. Section Title Doc Link 20009392 Disease Relevance 0.49 Pain Relevance 0.14
Proliferation was dependent on cell contact and on major histocompatibility complex (MHC) class II and CD40-CD154 (CD40 ligand) signaling.
Regulation (dependent) of CD154
3) Confidence 0.44 Published 2005 Journal Invest. Ophthalmol. Vis. Sci. Section Body Doc Link 16249464 Disease Relevance 0.07 Pain Relevance 0
The IgM-ELISA was neither specific nor sensitive.
Neg (neither) Regulation (sensitive) of IgM
4) Confidence 0.26 Published 1992 Journal Trans. R. Soc. Trop. Med. Hyg. Section Abstract Doc Link 1287934 Disease Relevance 1.24 Pain Relevance 0.07
OBJECTIVE: To determine the effect of Helicobacter pylori (H. pylori) eradication on blood levels of soluble CD40 ligand, leptin, oxidative stress and body composition in patients with dyspepsia infected with H. pylori.
Spec (determine) Regulation (effect) of CD40 ligand in body associated with stress, ulcers and nud
5) Confidence 0.26 Published 2009 Journal Intern. Med. Section Abstract Doc Link 20009392 Disease Relevance 0.60 Pain Relevance 0.12
Serum values of soluble CD40 ligand (sCD40L), interleukin-6 (IL-6), tumor necrosis factor-alpha (TNF-alpha), soluble intercellular adhesion molecule-1 (sICAM-1), and C-reactive protein (CRP) were measured.
Regulation (values) of CD40 ligand associated with necrosis, cancer and adhesions
6) Confidence 0.26 Published 2006 Journal J Cardiovasc Magn Reson Section Abstract Doc Link 17060099 Disease Relevance 0.60 Pain Relevance 0.19
Diagnostic values of anti-MCV, anti-CCP2, and IgM-RF are described as sensitivity and specificity with 95% confidence interval (CI).
Regulation (values) of IgM
7) Confidence 0.26 Published 2006 Journal Arthritis Res Ther Section Body Doc Link PMC1779400 Disease Relevance 0 Pain Relevance 0
Changes in Leptin, Adhesion Markers, CD40L, Blood Pressure, and Food Record Data
Regulation (Changes) of CD40L in Blood associated with adhesions
8) Confidence 0.26 Published 2010 Journal Nutr J Section Body Doc Link PMC2841082 Disease Relevance 0.32 Pain Relevance 0.03
In a large percentage of humans, experimental inoculation with a killed vaccine results in an early IgM response that wanes and is undetectable by 4 to 6 weeks, but this is not a model for natural infection (26).
Regulation (response) of IgM associated with infection
9) Confidence 0.25 Published 2002 Journal Emerging Infectious Diseases Section Body Doc Link PMC2732454 Disease Relevance 1.38 Pain Relevance 0.04
Several studies on myelin proteins in the PNS have indicated that the L2/HNK-1 epitope, which is believed to be both a ligand for cellular adhesion and a target for autoimmune monoclonal IgM neuritis, may be found on heretofore unidentified proteins with a molecular mass of 19-28 kDa.
Regulation (target) of IgM in HNK-1 associated with neuritis and adhesions
10) Confidence 0.22 Published 1993 Journal J. Neurochem. Section Abstract Doc Link 7693873 Disease Relevance 0.64 Pain Relevance 0.10
HHV-6 A- or B-specific P41 antigens do not reveal virus variant-specific IgG or IgM responses in human serum.
Regulation (responses) of IgM
11) Confidence 0.20 Published 2002 Journal J. Med. Virol. Section Title Doc Link 11793393 Disease Relevance 0.63 Pain Relevance 0.24
The daily samples were used to determine the sensitivity of IgM serology on each day of illness.
Spec (determine) Regulation (sensitivity) of IgM
12) Confidence 0.15 Published 2010 Journal PLoS Neglected Tropical Diseases Section Body Doc Link PMC2907414 Disease Relevance 0.65 Pain Relevance 0.07
The concentrations of the serum immunoglobulins, IgG, IgA, and IgM, were previously determined in 200 patients with juvenile rheumatoid arthritis, which showed abnormality in the distribution of these immunoglobulins in JIA10).
Regulation (concentrations) of IgM in juvenile associated with rheumatoid arthritis
13) Confidence 0.11 Published 2010 Journal Korean Journal of Pediatrics Section Body Doc Link PMC3012272 Disease Relevance 1.80 Pain Relevance 0.34
An example of this is found with VZV, which shows an IgM response upon reactivation [40].
Regulation (response) of IgM associated with herpes zoster
14) Confidence 0.11 Published 2005 Journal Virol J Section Body Doc Link PMC1243244 Disease Relevance 1.21 Pain Relevance 0
AHI: apnea-hypopnea index; BMI: body mass index; CRP: C-reactive protein; CV: coefficient of variation; ELISA: enzyme-linked immunosorbent assay; HOMA: homeostasis model assessment; HOMA-B: HOMA estimate of steady state beta-cell function; HOMA-IR: HOMA estimate of steady state insulin resistance; HOMA-IS:HOMA estimate of steady state insulin sensitivity; IGM: impaired glucose metabolism; IQR: interquartile range; IL-1ß: interleukin-1ß; IL-6: interleukin-6; IL-8: interleukin-8; LowSaO2: mean low oxyhemoglobin saturation during sleep; MeanSaO2: mean oxyhemoglobin saturation during sleep; MinSaO2: minimum oxyhemoglobin saturation during sleep; NGM: normal glucose metabolism; NREM: non-rapid eye movement; ODI: number of oxyhemoglobin desaturation events ?
Regulation (sensitivity) of IGM in eye associated with apnoea, obesity, insulin resistance and sleep disorders
15) Confidence 0.08 Published 2010 Journal Cardiovasc Diabetol Section Body Doc Link PMC3002325 Disease Relevance 1.16 Pain Relevance 0.03
Expression of Tax in primary ovine B lymphocytes, which are dependent on CD154 and interleukin-4, impacts cell proliferation and survival leading to cytokine independent growth [202].
Regulation (dependent) of CD154 in B lymphocytes associated with cytokine
16) Confidence 0.07 Published 2007 Journal Retrovirology Section Body Doc Link PMC1839114 Disease Relevance 0.12 Pain Relevance 0.05
IgM, IgG, and IgA response to enterobacteria in patients with ankylosing spondylitis in southern India.
Regulation (response) of IgM associated with spinal inflammation
17) Confidence 0.06 Published 2002 Journal Ann. N. Y. Acad. Sci. Section Title Doc Link 12021151 Disease Relevance 1.11 Pain Relevance 0.65
The most frequent changes were in the IgM levels.
Regulation (changes) of IgM
18) Confidence 0.06 Published 2010 Journal Clinical and Developmental Immunology Section Body Doc Link PMC3004381 Disease Relevance 0 Pain Relevance 0.03
A marked selective effect of IM treatment on serum IgM level in one patient has been reported by Nagasawa and Mizutan [25].
Regulation (effect) of IgM
19) Confidence 0.06 Published 2010 Journal Clinical and Developmental Immunology Section Body Doc Link PMC3004381 Disease Relevance 0.28 Pain Relevance 0
These observations suggest that important relationships exist between local IL-6 and IgA2, IgM, and IgG3 responses in human small intestinal luminal secretions.
Regulation (responses) of IgM
20) Confidence 0.06 Published 1998 Journal Dig. Dis. Sci. Section Abstract Doc Link 9512143 Disease Relevance 0.21 Pain Relevance 0.10

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox