INT51532

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Context Info
Confidence 0.50
First Reported 1994
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 1.72
Pain Relevance 0.55

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (Sult1a1) response to stress (Sult1a1) cytoplasm (Sult1a1)
Sult1a1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Paracetamol 6 94.76 High High
Bile 1 50.88 Quite High
antiepileptic Drug 33 34.36 Quite Low
pregabalin 4 24.56 Low Low
Gabapentin 6 23.24 Low Low
Glutamate 4 9.92 Low Low
GABA receptor 2 6.08 Low Low
gABA 16 5.00 Very Low Very Low Very Low
Lamotrigine 10 5.00 Very Low Very Low Very Low
imagery 10 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Acidosis 1 95.76 Very High Very High Very High
Syndrome 140 94.20 High High
Infantile Spasms 9 89.12 High High
Myoclonic Epilepsies 3 84.72 Quite High
Intrahepatic Cholestasis 3 75.00 Quite High
Convulsion 125 74.32 Quite High
Gallstones 2 68.28 Quite High
Partial Seizures 4 61.28 Quite High
Epilepsy 97 56.72 Quite High
Cognitive Disorder 6 54.72 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Sulphotransferase activity decreased during pregnancy compared with repeat measurements post partum (p < 0.005) and compared with non-pregnant individuals (p < 0.05).
Negative_regulation (decreased) of Sulphotransferase
1) Confidence 0.50 Published 1994 Journal J. Hepatol. Section Abstract Doc Link 7699239 Disease Relevance 0.27 Pain Relevance 0.55
STM, already used as early as the 1960s (Garland and Sumner 1964), is a carbonic anhydrase inhibitor responsible, at least partly, for beneficial effects on epileptiform activity secondary to intraneuronal acidosis.
Negative_regulation (inhibitor) of STM associated with acidosis
2) Confidence 0.05 Published 2008 Journal Neuropsychiatric Disease and Treatment Section Body Doc Link PMC2646636 Disease Relevance 1.45 Pain Relevance 0

General Comments

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