INT51583

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Context Info
Confidence 0.24
First Reported 1995
Last Reported 2006
Negated 0
Speculated 0
Reported most in Abstract
Documents 5
Total Number 5
Disease Relevance 2.30
Pain Relevance 1.11

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

mitochondrion (Gbf1) vesicle-mediated transport (Gbf1) peroxisome (Gbf1)
intracellular (Gbf1) molecular_function (Gbf1) biological_process (Gbf1)
Anatomy Link Frequency
blood 2
plasma 1
sensory nerves 1
Gbf1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
aspirin 20 99.50 Very High Very High Very High
cytokine 2 99.48 Very High Very High Very High
Cholecystokinin 19 97.54 Very High Very High Very High
Somatostatin 2 91.24 High High
antagonist 3 83.36 Quite High
spastic colon 1 76.48 Quite High
qutenza 6 75.00 Quite High
Inflammation 1 34.64 Quite Low
cINOD 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Ulcers 14 97.88 Very High Very High Very High
Cancer 1 96.72 Very High Very High Very High
Necrosis 1 96.48 Very High Very High Very High
Peptic Ulcer 5 91.40 High High
Urological Neuroanatomy 1 89.44 High High
Shock 2 84.28 Quite High
Stress 8 82.40 Quite High
Increased Venous Pressure Under Development 3 79.04 Quite High
Irritable Bowel Syndrome /

Irritable Bowel Syndrome Super

1 76.68 Quite High
Functional Bowel Disorder 1 76.48 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
CONCLUSIONS: The stomach is able to adapt to repeated stress insults by enhancing GBF and DNA synthesis, and this adaptation is mediated, at least in part, by sensory nerves and EGF.


Gene_expression (synthesis) of GBF in sensory nerves
1) Confidence 0.24 Published 1995 Journal Scand. J. Gastroenterol. Section Body Doc Link 7701252 Disease Relevance 0 Pain Relevance 0
In contrast, CCK-8, which stimulated gastric acid secretion, failed to affect the lesions induced by acidified ASA and the decrease in the GBF produced by this ulcerogen.
Gene_expression (produced) of GBF associated with aspirin and cholecystokinin
2) Confidence 0.09 Published 1998 Journal J. Clin. Gastroenterol. Section Abstract Doc Link 9872509 Disease Relevance 0.16 Pain Relevance 0.65
Number of gastric lesions, gastric mucosal blood flow (GBF), malondialdehyde (MDA) content, and RT-PCR expression of HSP70 mRNA were determined.
Gene_expression (expression) of GBF in blood
3) Confidence 0.08 Published 2002 Journal Digestion Section Body Doc Link 12481162 Disease Relevance 0.17 Pain Relevance 0
The area of ASA-induced gastric lesions, gastric blood flow (GBF), expression of mRNA and protein of leptin and plasma leptin, gastrin, interleukin-1beta, and tumor necrosis factor-alpha levels were examined.
Gene_expression (expression) of GBF in plasma associated with aspirin, necrosis and cancer
4) Confidence 0.03 Published 2004 Journal J. Pharmacol. Exp. Ther. Section Abstract Doc Link 15024038 Disease Relevance 0.83 Pain Relevance 0.33
Weight, damage area, gastric blood flow (GBF) (H2 clearance), expression of mRNA for cytokines IL-beta, TNF-alpha (ELISA) were evaluated.
Gene_expression (expression) of GBF in blood associated with cytokine
5) Confidence 0.02 Published 2006 Journal J. Physiol. Pharmacol. Section Abstract Doc Link 17242486 Disease Relevance 1.07 Pain Relevance 0.13

General Comments

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