INT51667

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Context Info
Confidence 0.20
First Reported 1995
Last Reported 2010
Negated 1
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 0.10
Pain Relevance 1.06

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

molecular_function (Cfp) cellular_component (Cfp) biological_process (Cfp)
Cfp (Rattus norvegicus)
Pain Link Frequency Relevance Heat
opioid receptor 26 99.64 Very High Very High Very High
antagonist 7 98.22 Very High Very High Very High
narcan 33 95.36 Very High Very High Very High
Kappa opioid receptor 3 94.88 High High
opiate 1 89.80 High High
amygdala 55 75.80 Quite High
Intracerebroventricular 1 74.24 Quite High
mu opioid receptor 2 73.24 Quite High
agonist 2 59.48 Quite High
Opioid 13 50.00 Quite Low
Disease Link Frequency Relevance Heat
Anxiety Disorder 33 98.48 Very High Very High Very High
Urological Neuroanatomy 4 50.00 Quite Low
Shock 6 5.00 Very Low Very Low Very Low
Nociception 2 5.00 Very Low Very Low Very Low
Phobia 1 5.00 Very Low Very Low Very Low
Stupor 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Antagonists alone produced stimulation of PFC following i.p. administration in the rat, but did not affect PFC response upon in vitro treatment.
Neg (not) Regulation (affect) of Neg (not) Regulation (response) of PFC associated with antagonist
1) Confidence 0.20 Published 1995 Journal J. Neuroimmunol. Section Abstract Doc Link 7706440 Disease Relevance 0 Pain Relevance 0.59
These data argue that opioid receptors in the vlPAG are involved in regulating plasticity in the mPFC and BLA related to the extinction of fear conditioning.
Regulation (involved) of Regulation (regulating) of mPFC associated with anxiety disorder and opioid receptor
2) Confidence 0.01 Published 2010 Journal Frontiers in Behavioral Neuroscience Section Body Doc Link PMC2927240 Disease Relevance 0.10 Pain Relevance 0.47

General Comments

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