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Context Info
Confidence 0.11
First Reported 1995
Last Reported 2011
Negated 0
Speculated 0
Reported most in Body
Documents 3
Total Number 3
Disease Relevance 2.80
Pain Relevance 0.08

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

transport (Cog1) Golgi apparatus (Cog1)
Anatomy Link Frequency
liver 1
Cog1 (Mus musculus)
Pain Link Frequency Relevance Heat
Angina 2 84.76 Quite High
Bile 10 7.12 Low Low
cva 9 5.00 Very Low Very Low Very Low
withdrawal 3 5.00 Very Low Very Low Very Low
peptic ulcer disease 3 5.00 Very Low Very Low Very Low
abdominal pain 2 5.00 Very Low Very Low Very Low
nud 2 5.00 Very Low Very Low Very Low
aspirin 1 5.00 Very Low Very Low Very Low
depression 1 5.00 Very Low Very Low Very Low
Inflammatory response 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Disorder Of Lipid Metabolism 62 99.92 Very High Very High Very High
Hyperlipidemia 4 99.20 Very High Very High Very High
Insulin Resistance 5 94.76 High High
Dyslipidemia /

Combined Dyslipidemia

13 85.56 High High
Metabolic Syndrome 5 84.76 Quite High
Atherosclerosis 35 82.96 Quite High
Hyperinsulinism 2 81.32 Quite High
Sprains And Strains 4 73.32 Quite High
Lower Respiratory Tract Infection 1 63.64 Quite High
Toxicity 5 52.12 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Lipoproteins consist of apolipoproteins, phospholipids, cholesterol, triacyclglyerols, and cholesteryl esters and it is these that define the particle's buoyant density and enables their separation into four major classes: high-density lipoprotein, low-density lipoprotein, very low-density lipoprotein (HDL, LDL, and VLDL, resp.), and chylomicrons.
Localization (very) of low-density lipoprotein associated with disorder of lipid metabolism
1) Confidence 0.11 Published 2011 Journal Journal of Biomedicine and Biotechnology Section Body Doc Link PMC2975993 Disease Relevance 0.99 Pain Relevance 0
The hypertriglyceridemia is caused by an elevated synthesis and secretion of VLDL (very low density lipoprotein) in the liver and by reduced metabolism, mediated e.g. by lipoprotein lipase.
Localization (secretion) of low density lipoprotein in liver associated with hyperlipidemia
2) Confidence 0.03 Published 1995 Journal Herz Section Abstract Doc Link 7713475 Disease Relevance 1.21 Pain Relevance 0.08
Although the pharmacology of niacin is not fully understood, the primary effect is inhibition of the synthesis and secretion of hepatic very low-density lipoprotein cholesterol (VLDL-C) which reduces triglycerides and LDL-C (Grundy et al 1981; Knopp et al 1985).
Localization (secretion) of low-density lipoprotein
3) Confidence 0.02 Published 2005 Journal Vascular Health and Risk Management Section Body Doc Link PMC1993967 Disease Relevance 0.43 Pain Relevance 0

General Comments

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