INT51778

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.26
First Reported 1995
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 0.69
Pain Relevance 0.77

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

transport (Scn7a)
Anatomy Link Frequency
margin 2
Scn7a (Mus musculus)
Pain Link Frequency Relevance Heat
tetrodotoxin 25 99.98 Very High Very High Very High
imagery 5 98.90 Very High Very High Very High
Glutamate 1 81.52 Quite High
Glutamate receptor 3 80.28 Quite High
sodium channel 4 75.00 Quite High
antagonist 1 75.00 Quite High
lidocaine 1 52.64 Quite High
addiction 2 5.00 Very Low Very Low Very Low
Action potential 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Death 17 87.68 High High
Injury 6 85.36 High High
Drug Induced Neurotoxicity 1 80.72 Quite High
Hypoxia 3 74.88 Quite High
Muscular Dystrophy 6 5.00 Very Low Very Low Very Low
Apoptosis 1 5.00 Very Low Very Low Very Low
Dislocations 1 5.00 Very Low Very Low Very Low
Necrosis 1 5.00 Very Low Very Low Very Low
Disease 1 5.00 Very Low Very Low Very Low
Chronic Disease 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Fluorescent imaging using the Na(+)-selective dye SBFI confirmed that TTX attenuated the increase in intracellular free Na+ induced by oxygen-glucose deprivation.
Negative_regulation (attenuated) of Positive_regulation (increase) of Na associated with tetrodotoxin and imagery
1) Confidence 0.26 Published 1995 Journal J. Pharmacol. Exp. Ther. Section Abstract Doc Link 7714811 Disease Relevance 0.69 Pain Relevance 0.77
On the other hand, the finding that inactivation times were consistently and by a big margin larger in mdx5cv cells enables to explain the increased stimulated inward Na+ current in spite of the decreased Nav1.4 expression levels.
Negative_regulation (decreased) of Positive_regulation (increased) of Na in margin
2) Confidence 0.04 Published 2008 Journal The Journal of General Physiology Section Body Doc Link PMC2483333 Disease Relevance 0 Pain Relevance 0

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox