INT51953

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Context Info
Confidence 0.36
First Reported 1993
Last Reported 1995
Negated 0
Speculated 0
Reported most in Abstract
Documents 2
Total Number 2
Disease Relevance 0.73
Pain Relevance 0.59

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (Gnrhr) signal transducer activity (Gnrhr)
Anatomy Link Frequency
sella 2
Gnrhr (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Morphine 5 99.42 Very High Very High Very High
tolerance 1 99.18 Very High Very High Very High
Clonidine 1 88.56 High High
Hippocampus 1 87.80 High High
Intracerebroventricular 1 46.72 Quite Low
Disease Link Frequency Relevance Heat
Growth Problems 2 100.00 Very High Very High Very High
Growth Hormone Deficiency 1 100.00 Very High Very High Very High
Empty Sella Syndrome 1 99.64 Very High Very High Very High
Intrauterine Growth Retardation 1 94.28 High High
Syndrome 4 90.24 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
When tolerance to morphine was developed, the level of growth hormone-binding was restored to control level.
Positive_regulation (restored) of growth hormone Binding (binding) of associated with tolerance and morphine
1) Confidence 0.36 Published 1995 Journal Neurosci. Lett. Section Abstract Doc Link 7724051 Disease Relevance 0 Pain Relevance 0.50
Seven of 12 were normal and 4/12, one with empty sella, had "classical" growth hormone deficiency with extreme short stature, markedly delayed skeletal maturation and subnormal growth hormone secretion in response to provocative stimuli.
Positive_regulation (response) of growth hormone Binding (deficiency) of in sella associated with growth hormone deficiency, growth problems and empty sella syndrome
2) Confidence 0.30 Published 1993 Journal Am. J. Med. Genet. Section Abstract Doc Link 8291522 Disease Relevance 0.73 Pain Relevance 0.09

General Comments

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