INT52188

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Context Info
Confidence 0.16
First Reported 1994
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 5
Disease Relevance 1.56
Pain Relevance 1.63

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

structural molecule activity (Des) cytoskeleton (Des) intracellular (Des)
cytoplasm (Des)
Anatomy Link Frequency
corpus 1
Des (Rattus norvegicus)
Pain Link Frequency Relevance Heat
bradykinin 22 100.00 Very High Very High Very High
Hyperalgesia 8 99.96 Very High Very High Very High
Inflammatory stimuli 1 98.88 Very High Very High Very High
B1 receptor 1 97.72 Very High Very High Very High
agonist 5 97.24 Very High Very High Very High
Thermal hyperalgesia 2 92.60 High High
Pain 4 89.68 High High
Inflammation 10 88.36 High High
medulla 4 82.40 Quite High
withdrawal 3 77.60 Quite High
Disease Link Frequency Relevance Heat
Hyperalgesia 10 99.96 Very High Very High Very High
INFLAMMATION 10 98.88 Very High Very High Very High
Obesity 76 97.08 Very High Very High Very High
Pain 4 89.68 High High
Stress Incontinence 12 84.92 Quite High
Reprotox - General 3 12 82.40 Quite High
Arthritis 1 75.52 Quite High
Diabetes Mellitus 8 65.68 Quite High
Hyperlipidemia 4 32.88 Quite Low
Cancer 8 30.48 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
transcripts were significantly upregulated with DES and reduced by antiestrogen ICI 182, 780.
Positive_regulation (upregulated) of DES
1) Confidence 0.16 Published 2008 Journal PPAR Research Section Abstract Doc Link PMC2519140 Disease Relevance 0.08 Pain Relevance 0
DES accumulated fat in the corpus cavernous penis [5–8]
Positive_regulation (accumulated) of DES in corpus
2) Confidence 0.16 Published 2008 Journal PPAR Research Section Body Doc Link PMC2519140 Disease Relevance 0.48 Pain Relevance 0.18
in the aforementioned DES-penile rat
Positive_regulation (aforementioned) of DES
3) Confidence 0.16 Published 2008 Journal PPAR Research Section Body Doc Link PMC2519140 Disease Relevance 0.19 Pain Relevance 0
Similarly, DES induced slightly over seven-fold-increase (7.1) in PPAR?
Positive_regulation (induced) of DES
4) Confidence 0.15 Published 2008 Journal PPAR Research Section Body Doc Link PMC2519140 Disease Relevance 0 Pain Relevance 0
The induction of des-Arg9-bradykinin-mediated hyperalgesia in the rat by inflammatory stimuli.
Positive_regulation (induction) of des-Arg9-bradykinin-mediated associated with hyperalgesia, bradykinin and inflammatory stimuli
5) Confidence 0.03 Published 1994 Journal Braz. J. Med. Biol. Res. Section Title Doc Link 7749369 Disease Relevance 0.81 Pain Relevance 1.45

General Comments

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