INT52203

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.51
First Reported 1993
Last Reported 2009
Negated 2
Speculated 0
Reported most in Abstract
Documents 5
Total Number 6
Disease Relevance 3.27
Pain Relevance 4.48

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleoplasm (TCEA1) nucleolus (TCEA1) nucleus (TCEA1)
DNA binding (TCEA1)
Anatomy Link Frequency
ACC 3
neurons 2
lip 2
SII 1
TCEA1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Somatosensory cortex 11 100.00 Very High Very High Very High
Anterior cingulate cortex 6 100.00 Very High Very High Very High
nMDA receptor 1 99.84 Very High Very High Very High
Trigeminal neuralgia 18 99.28 Very High Very High Very High
nociceptor 1 98.94 Very High Very High Very High
Pain 32 96.92 Very High Very High Very High
antagonist 1 92.56 High High
Pain score 2 83.00 Quite High
imagery 2 81.92 Quite High
positron emission tomography 2 76.20 Quite High
Disease Link Frequency Relevance Heat
Nociception 3 99.84 Very High Very High Very High
Headache 18 99.28 Very High Very High Very High
Pain 24 96.92 Very High Very High Very High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
These results suggest that fluvoxamine specifically reduced activation of the ACC and SII, which are areas concerned with the affective and integrative components of pain.
Negative_regulation (reduced) of Positive_regulation (activation) of SII in ACC associated with pain, somatosensory cortex and anterior cingulate cortex
1) Confidence 0.51 Published 2003 Journal Neuroreport Section Abstract Doc Link 12858034 Disease Relevance 0.48 Pain Relevance 0.92
For lip stimulation SI and SII activations were reduced in patients with TN on the contra- but not on the ipsilateral side to the stimulus.
Neg (not) Negative_regulation (reduced) of Positive_regulation (activations) of SII in lip associated with trigeminal neuralgia
2) Confidence 0.37 Published 2009 Journal Hum Brain Mapp Section Abstract Doc Link 19365802 Disease Relevance 0.93 Pain Relevance 1.09
However, SI and SII activations, but not thalamic activations, were significantly reduced in patients as compared to controls.
Negative_regulation (reduced) of Neg (not) Positive_regulation (activations) of SII
3) Confidence 0.32 Published 2009 Journal Hum Brain Mapp Section Abstract Doc Link 19365802 Disease Relevance 1.14 Pain Relevance 1.30
[Influence of cooling motor cortex on the inhibitory effect of stimulation of SII on nociceptive responses in ILN neurons].
Negative_regulation (effect) of Positive_regulation (stimulation) of SII in neurons associated with nociception and nociceptor
4) Confidence 0.32 Published 1994 Journal Zhen Ci Yan Jiu Section Title Doc Link 7750169 Disease Relevance 0.25 Pain Relevance 0.10
These results suggest that fluvoxamine specifically reduced activation of the ACC and SII, which are areas concerned with the affective and integrative components of pain.
Negative_regulation (reduced) of in SII Positive_regulation (activation) of SII in ACC associated with pain, somatosensory cortex and anterior cingulate cortex
5) Confidence 0.17 Published 2003 Journal Neuroreport Section Abstract Doc Link 12858034 Disease Relevance 0.48 Pain Relevance 0.92
Cortical intraventricular injection of D-2-amino-5-phosphonovalerate (APV) and DL-2-amino-7-phosphonoheptanoic acid (APH) prevented induction of the potentiation in SII.
Negative_regulation (prevented) of Positive_regulation (induction) of SII
6) Confidence 0.02 Published 1993 Journal Brain Res. Section Abstract Doc Link 8096787 Disease Relevance 0 Pain Relevance 0.13

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox