INT52239

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Context Info
Confidence 0.63
First Reported 1995
Last Reported 1998
Negated 0
Speculated 0
Reported most in Abstract
Documents 3
Total Number 3
Disease Relevance 0
Pain Relevance 0.05

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (Jun) extracellular region (Penk) aging (Jun)
nucleus (Jun) DNA binding (Jun) transcription factor binding (Jun)
Anatomy Link Frequency
striatum 4
Jun (Rattus norvegicus)
Penk (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Nucleus accumbens 2 52.80 Quite High
Enkephalin 5 25.00 Low Low
Neuropeptide 1 25.00 Low Low
Disease Link Frequency Relevance Heat
Pheochromocytoma 1 48.40 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
These results indicate a cooperative effect of AP1 and CREB on PENK transcription.
AP1 Regulation (effect) of Transcription (transcription) of PENK
1) Confidence 0.63 Published 1998 Journal DNA Cell Biol. Section Abstract Doc Link 9502431 Disease Relevance 0 Pain Relevance 0
The effect of a single injection of caffeine on the expression of c-fos, c-jun, junB, and junD, on activator protein 1 (AP-1) and on the levels of preproenkephalin mRNA in rat striatum was studied.
activator protein 1 Regulation (effect) of Transcription (levels) of preproenkephalin mRNA in striatum
2) Confidence 0.12 Published 1995 Journal J. Neurosci. Section Abstract Doc Link 7751931 Disease Relevance 0 Pain Relevance 0.03
The effect of a single injection of caffeine on the expression of c-fos, c-jun, junB, and junD, on activator protein 1 (AP-1) and on the levels of preproenkephalin mRNA in rat striatum was studied.
AP-1 Regulation (effect) of Transcription (levels) of preproenkephalin mRNA in striatum
3) Confidence 0.12 Published 1995 Journal J. Neurosci. Section Abstract Doc Link 7751931 Disease Relevance 0 Pain Relevance 0.03

General Comments

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