INT52330

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Context Info
Confidence 0.45
First Reported 1993
Last Reported 2008
Negated 1
Speculated 0
Reported most in Abstract
Documents 4
Total Number 5
Disease Relevance 0.72
Pain Relevance 1.00

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Anatomy Link Frequency
neural 2
neuronal 1
perikaryons 1
Synm (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Central nervous system 2 99.96 Very High Very High Very High
fibrosis 31 96.48 Very High Very High Very High
Raphe 3 96.16 Very High Very High Very High
Locus ceruleus 3 94.80 High High
Clonidine 2 93.60 High High
Peripheral nervous system 2 89.44 High High
agonist 2 78.96 Quite High
Neuropeptide 2 77.20 Quite High
vagus nerve 1 73.16 Quite High
cytokine 3 59.08 Quite High
Disease Link Frequency Relevance Heat
Injury 16 98.00 Very High Very High Very High
Cirrhosis 51 96.80 Very High Very High Very High
Fibrosis 24 84.88 Quite High
Apoptosis 2 60.12 Quite High
Pulmonary Fibrosis 2 35.52 Quite Low
Cytomegalovirus Infection 19 27.04 Quite Low
Increased Venous Pressure Under Development 2 25.00 Low Low
Migraine Disorders 1 25.00 Low Low
Liver Disease 2 5.00 Very Low Very Low Very Low
Rigor 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Mature neurons, whose perikaryons and axons are entirely located within the central nervous system, express the low molecular mass neurofilament protein and not the 57,000 mol. wt intermediate filament protein called "peripherin".
Neg (not) Gene_expression (express) of intermediate filament protein in perikaryons associated with central nervous system
1) Confidence 0.45 Published 1993 Journal Neuroscience Section Abstract Doc Link 8450965 Disease Relevance 0 Pain Relevance 0.37
Impressively, a single injection of adenovirus expressing the truncated receptor, given prior to DMN administration, appeared to prevent both hepatic injury and the development of hepatic fibrosis.
Gene_expression (expressing) of DMN associated with fibrosis, cirrhosis and injury
2) Confidence 0.13 Published 2003 Journal BMC Gastroenterol Section Body Doc Link PMC270053 Disease Relevance 0.72 Pain Relevance 0.30
Immunocytochemical and Western blot assays for nestin expression indicated that almost all of the cells available for recording expressed this intermediate filament protein, which is generally accepted as a marker for uncommitted embryonic neural progenitor cells.
Gene_expression (expressed) of intermediate filament protein in neural
3) Confidence 0.05 Published 2008 Journal PLoS ONE Section Abstract Doc Link PMC2225502 Disease Relevance 0 Pain Relevance 0
Immunocytochemical assays for nestin indicated that nearly all (>99%) cells expressed this intermediate filament protein, which is generally associated with undifferentiated neural progenitor cells (Figure 2 A).
Gene_expression (expressed) of intermediate filament protein in neural
4) Confidence 0.04 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2225502 Disease Relevance 0 Pain Relevance 0
The results emphasize that during cardiovascular regulation NPY receptors can control neuronal gene expression in the NTS-dmnX complex via c-fos and that stimulation of alpha 2-adrenoceptors can attenuate NPY receptor transduction also in terms of induction of c-Fos IR in the NTS-dmnX complex via an antagonistic alpha 2/NPY receptor interaction.
Gene_expression (expression) of dmnX in neuronal
5) Confidence 0.03 Published 1995 Journal Neuroreport Section Abstract Doc Link 7756634 Disease Relevance 0 Pain Relevance 0.33

General Comments

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