INT52348

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Context Info
Confidence 0.44
First Reported 1995
Last Reported 2009
Negated 1
Speculated 0
Reported most in Body
Documents 7
Total Number 8
Disease Relevance 4.18
Pain Relevance 0.25

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Anatomy Link Frequency
vessels 2
RLN 1
lymphoblasts 1
CHM (Homo sapiens)
Pain Link Frequency Relevance Heat
imagery 80 77.76 Quite High
cva 19 75.84 Quite High
anesthesia 10 70.56 Quite High
cytokine 12 21.40 Low Low
aspirin 4 5.00 Very Low Very Low Very Low
Spinal cord 4 5.00 Very Low Very Low Very Low
Central nervous system 2 5.00 Very Low Very Low Very Low
epidural 2 5.00 Very Low Very Low Very Low
ischemia 2 5.00 Very Low Very Low Very Low
chemokine 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Choroideremia 332 100.00 Very High Very High Very High
Intracranial Embolism 6 99.44 Very High Very High Very High
Injury 473 99.00 Very High Very High Very High
Heart Failure 14 97.84 Very High Very High Very High
Whiplash Injuries 2 97.56 Very High Very High Very High
Myocardial Infarction 5 86.40 High High
Congenital Anomalies 6 84.60 Quite High
Embolism 7 83.96 Quite High
Targeted Disruption 8 76.96 Quite High
Vascular System Injuries 30 76.52 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
For example, Rab27 is under-prenylated in lymphoblasts from the CHM patients and probably preferentially requires REP-1 [8].
Positive_regulation (requires) of REP-1 in lymphoblasts associated with choroideremia
1) Confidence 0.44 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2793004 Disease Relevance 0.84 Pain Relevance 0
Differences in the regulation of secretion between the different cell types with reduced/absent levels of REP-1 could explain the tissue specific degeneration that occurs in choroideremia.
Positive_regulation (occurs) of choroideremia associated with choroideremia
2) Confidence 0.41 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2793004 Disease Relevance 0.49 Pain Relevance 0
In one interesting case, Kilic et al used TCD to evaluate patients suspected of having a traumatic CCF [100].
Positive_regulation (used) of TCD associated with heart failure
3) Confidence 0.26 Published 2007 Journal World J Emerg Surg Section Body Doc Link PMC1796545 Disease Relevance 1.14 Pain Relevance 0.07
In this study, 47 patients with clinical signs of whiplash underwent TCD within a month of their injury and at 6 months post-injury.
Positive_regulation (underwent) of TCD associated with injury
4) Confidence 0.24 Published 2007 Journal World J Emerg Surg Section Body Doc Link PMC1796545 Disease Relevance 1.14 Pain Relevance 0.07
TCD has also been utilized in detecting cerebral emboli, improper cannulation or cross clamping of aortic arch vessels.
Positive_regulation (utilized) of TCD in vessels associated with intracranial embolism
5) Confidence 0.22 Published 2006 Journal Cardiovasc Ultrasound Section Abstract Doc Link PMC1764902 Disease Relevance 0.19 Pain Relevance 0
TCD has also been utilized in detecting cerebral emboli, improper cannulation or cross clamping of aortic arch vessels.
Positive_regulation (utilized) of TCD in vessels associated with intracranial embolism
6) Confidence 0.22 Published 2006 Journal Cardiovasc Ultrasound Section Body Doc Link PMC1764902 Disease Relevance 0.22 Pain Relevance 0.07
The current TCD software with an automatic emboli detection and count is not implemented in the echocardiography devices.
Neg (not) Positive_regulation (implemented) of TCD
7) Confidence 0.05 Published 2008 Journal Cases J Section Body Doc Link PMC2542348 Disease Relevance 0.16 Pain Relevance 0.04
Furthermore, bilateral section of the ExSLN in five dogs significantly reduced tidal TCD by 48.7 +/- 24.4% (P < 0.05), and bilateral section of both the ExSLN and RLN resulted in slight phasic inward TCD (-0.06 +/- 0.05 mm).
Positive_regulation (resulted) of TCD in RLN
8) Confidence 0.02 Published 1995 Journal J. Appl. Physiol. Section Abstract Doc Link 7759411 Disease Relevance 0 Pain Relevance 0

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