INT52391

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Context Info
Confidence 0.26
First Reported 1995
Last Reported 1997
Negated 0
Speculated 0
Reported most in Abstract
Documents 2
Total Number 2
Disease Relevance 0.28
Pain Relevance 0.98

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (OPRD1) cytoplasm (OPRD1) signal transducer activity (OPRD1)
Anatomy Link Frequency
NG108-15 2
OPRD1 (Homo sapiens)
Pain Link Frequency Relevance Heat
opioid receptor 14 100.00 Very High Very High Very High
Enkephalin 3 99.90 Very High Very High Very High
agonist 1 96.52 Very High Very High Very High
Opioid 3 88.48 High High
opiate 1 84.48 Quite High
antagonist 1 83.92 Quite High
narcan 1 83.04 Quite High
Analgesic 1 25.00 Low Low
Disease Link Frequency Relevance Heat
Neuroblastoma 1 99.32 Very High Very High Very High
Glioma 1 98.68 Very High Very High Very High
Bordatella Infection 2 79.36 Quite High
Repression 1 34.48 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The inhibitory response of [D-Pen2,D-Pen5]-enkephalin was dependent on the expression of the delta-opioid receptor and exhibited an EC50 of 1 nM.
Regulation (dependent) of Gene_expression (expression) of delta-opioid associated with opioid receptor and enkephalin
1) Confidence 0.26 Published 1995 Journal J. Neurochem. Section Abstract Doc Link 7760050 Disease Relevance 0.08 Pain Relevance 0.81
The effects of activation of the adenylyl cyclase-protein kinase A pathway on the expression of delta-opioid receptor mRNA in the NG108-15 neuroblastoma x glioma cell line has been investigated.
Regulation (effects) of Gene_expression (expression) of delta-opioid receptor mRNA in NG108-15 associated with neuroblastoma, opioid receptor and glioma
2) Confidence 0.05 Published 1997 Journal J. Neurochem. Section Abstract Doc Link 9003047 Disease Relevance 0.20 Pain Relevance 0.16

General Comments

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