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Context Info
Confidence 0.20
First Reported 1995
Last Reported 1997
Negated 0
Speculated 0
Reported most in Abstract
Documents 2
Total Number 2
Disease Relevance 0.16
Pain Relevance 1.34

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (HTR1D, Gh) mitochondrion (Gh) signal transducer activity (HTR1D)
cytosol (Gh) extracellular space (Gh) signal transduction (Gh)
HTR1D (Homo sapiens)
Gh (Mus musculus)
Pain Link Frequency Relevance Heat
Sumatriptan 21 99.64 Very High Very High Very High
agonist 2 97.84 Very High Very High Very High
Serotonin 2 87.36 High High
Clonidine 1 50.16 Quite High
Somatostatin 1 25.00 Low Low
Disease Link Frequency Relevance Heat
Obesity 2 83.28 Quite High
Acromegaly 1 75.00 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In normals, SU is able to decrease GH response to GHRH, thus confirming that 5-HT1D receptors are able to modulate GH secretion in normals.
5-HT1D Regulation (modulate) of Localization (secretion) of GH associated with sumatriptan
1) Confidence 0.20 Published 1997 Journal Recenti Prog Med Section Abstract Doc Link 9233053 Disease Relevance 0.07 Pain Relevance 0.68
We have taken advantage of a new selective 5-HT1D receptor agonist 3-[2-(dimethylamino)ethyl]-N-methyl-1H-indole-5-methanesulfonamide succinate, Sumatriptan, to evaluate the role of 5-HT1D receptors on GH secretion.
5-HT1D Regulation (role) of Localization (secretion) of GH associated with sumatriptan and agonist
2) Confidence 0.10 Published 1995 Journal J. Clin. Endocrinol. Metab. Section Abstract Doc Link 7775648 Disease Relevance 0.08 Pain Relevance 0.66

General Comments

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