INT52618

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Context Info
Confidence 0.33
First Reported 1994
Last Reported 2007
Negated 0
Speculated 0
Reported most in Abstract
Documents 3
Total Number 3
Disease Relevance 0.82
Pain Relevance 1.90

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Pdgfc) extracellular region (Pdgfc) nucleus (Pdgfc)
cytoplasm (Pdgfc)
Anatomy Link Frequency
spinal cord 2
SCDH 1
Pdgfc (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Spinal cord 8 100.00 Very High Very High Very High
Glutamate 7 100.00 Very High Very High Very High
Dorsal horn 3 100.00 Very High Very High Very High
GABAergic 2 100.00 Very High Very High Very High
nociceptor 1 100.00 Very High Very High Very High
Antinociceptive 2 99.32 Very High Very High Very High
Gabapentin 7 89.76 High High
Eae 3 87.20 High High
Lamotrigine 6 84.24 Quite High
Sciatic nerve 1 82.48 Quite High
Disease Link Frequency Relevance Heat
Nociception 2 99.30 Very High Very High Very High
Hypersensitivity 1 93.00 High High
Injury 3 87.20 High High
Urological Neuroanatomy 1 82.40 Quite High
Neuropathic Pain 3 75.00 Quite High
Pain 1 50.92 Quite High
Hyperalgesia 1 25.84 Quite Low
Overactive Bladder 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The highest doses of each of the agents were also assessed on formalin-induced nociceptive behaviors and on formalin-induced increases in extracellular glutamate (Glu) and aspartate (Asp) in the spinal cord dorsal horn (SCDH) of awake behaving rats using in vivo microdialysis.
Positive_regulation (increases) of spinal cord dorsal horn in SCDH associated with nociception, glutamate, dorsal horn and spinal cord
1) Confidence 0.33 Published 2007 Journal J. Neurochem. Section Abstract Doc Link 17241130 Disease Relevance 0.69 Pain Relevance 1.24
Activation of the c-fos proto-oncogene in the spinal cord following noxious stimulation of the urinary bladder.
Positive_regulation (Activation) of cord in spinal cord associated with nociceptor and spinal cord
2) Confidence 0.03 Published 1994 Journal Somatosens Mot Res Section Title Doc Link 7778409 Disease Relevance 0.13 Pain Relevance 0.34
In this study, the authors sought evidence for the involvement of alpha1 adrenoceptors in the antinociceptive effect of N2O and in activation of GABAergic neurons in the spinal cord.
Positive_regulation (activation) of cord in spinal cord associated with gabaergic, antinociceptive and spinal cord
3) Confidence 0.01 Published 2002 Journal Anesthesiology Section Abstract Doc Link 12459672 Disease Relevance 0 Pain Relevance 0.32

General Comments

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