INT52758

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Context Info
Confidence 0.57
First Reported 1995
Last Reported 1996
Negated 0
Speculated 0
Reported most in Abstract
Documents 2
Total Number 2
Disease Relevance 0.33
Pain Relevance 1.73

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (Sptan1) plasma membrane (Sptan1) cytoskeleton (Sptan1)
protein complex (Sptan1) cytoplasm (Sptan1)
Sptan1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
adenocard 8 100.00 Very High Very High Very High
agonist 5 99.82 Very High Very High Very High
opioid receptor 5 93.44 High High
Dopamine 4 91.20 High High
MU agonist 4 90.40 High High
Morphine 4 88.40 High High
antagonist 3 88.08 High High
Opioid 2 75.68 Quite High
dopamine receptor 3 75.00 Quite High
Disease Link Frequency Relevance Heat
Sprains And Strains 5 99.40 Very High Very High Very High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Furthermore, DT-II and DPDPE inhibit A2a adenosine-stimulated adenylyl cyclase (antagonized by NTB and BNTX, respectively), whereas DAMGO did not inhibit A2a adenosine-stimulated adenylyl cyclase activity.
Negative_regulation (inhibit) of Positive_regulation (stimulated) of A2a associated with adenocard
1) Confidence 0.57 Published 1995 Journal J. Neurochem. Section Abstract Doc Link 7790855 Disease Relevance 0 Pain Relevance 0.94
In contrast, the delta 2 agonist, DT-II, inhibited both D1 and A2a activated enzyme in all strains except DBA/2J, where DT-II did not inhibit D1-activated adenylyl cyclase.
Negative_regulation (inhibited) of Positive_regulation (activated) of A2a associated with agonist and sprains and strains
2) Confidence 0.41 Published 1996 Journal Brain Res. Section Abstract Doc Link 8738226 Disease Relevance 0.33 Pain Relevance 0.79

General Comments

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