INT52794

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Context Info
Confidence 0.31
First Reported 1995
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 3
Total Number 5
Disease Relevance 3.64
Pain Relevance 1.67

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoplasm (Btg3)
Anatomy Link Frequency
spinal cord 1
Btg3 (Mus musculus)
Pain Link Frequency Relevance Heat
rheumatoid arthritis 45 97.12 Very High Very High Very High
Spinal cord 1 96.68 Very High Very High Very High
tail-flick 6 94.88 High High
Fibrositis 21 84.64 Quite High
Cannabinoid 4 82.96 Quite High
antinociception 8 81.76 Quite High
Opioid 3 81.12 Quite High
Antinociceptive 4 79.12 Quite High
antagonist 2 75.72 Quite High
tolerance 7 75.00 Quite High
Disease Link Frequency Relevance Heat
Systemic Lupus Erythematosus 154 99.12 Very High Very High Very High
Autoimmune Disease 18 98.84 Very High Very High Very High
Disease 93 98.60 Very High Very High Very High
Dermatomyositis 15 98.28 Very High Very High Very High
Infection 4 97.44 Very High Very High Very High
Rheumatoid Arthritis 45 97.12 Very High Very High Very High
Malignant Neoplastic Disease 3 96.80 Very High Very High Very High
Rheumatic Diseases 59 86.72 High High
Sleep Disorders 21 84.64 Quite High
Frostbite 1 83.60 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
This lack of specificity of the ANA immunofluorescent pattern has been recognized previously, both for adults and children [8,10,11].
ANA Binding (recognized) of
1) Confidence 0.31 Published 2010 Journal Pediatr Rheumatol Online J Section Body Doc Link PMC2987328 Disease Relevance 0.73 Pain Relevance 0.05
As ANA tests are usually performed on children or adults with musculoskeletal or rheumatologic symptoms or signs, the frequency of ANA among clinic populations is more pertinent to our discussion than the situation in the normal population

ANA in clinic populations-ANA titers

ANA Binding (frequency) of
2) Confidence 0.31 Published 2010 Journal Pediatr Rheumatol Online J Section Body Doc Link PMC2987328 Disease Relevance 0.20 Pain Relevance 0.03
The Ki for the displacement of 3H-CP 55,940 binding by ANA and FA was 214 nM (+/- 45 S.E.M.) and 72 nM (+/- 5 S.E.M.), respectively, in pure spinal cord synaptosomes from the rat.
ANA Binding (binding) of in spinal cord associated with spinal cord
3) Confidence 0.31 Published 1995 Journal J. Pharmacol. Exp. Ther. Section Abstract Doc Link 7791096 Disease Relevance 0 Pain Relevance 1.33
It should also be remembered that ANA are associated not only with the classical autoimmune diseases, but also with infection [19], malignancy [20,21] and drugs (Table 1) [22].
ANA Binding (associated) of associated with malignant neoplastic disease, autoimmune disease and infection
4) Confidence 0.30 Published 2010 Journal Pediatr Rheumatol Online J Section Body Doc Link PMC2987328 Disease Relevance 1.38 Pain Relevance 0.14
Despite the presence of three manifestations or criteria for systemic lupus we did not consider that these patients had drug-induced SLE, but rather that they presented toxidermia associated with ANA.
ANA Binding (associated) of associated with systemic lupus erythematosus
5) Confidence 0.06 Published 2005 Journal Arthritis Res Ther Section Body Doc Link PMC1174953 Disease Relevance 1.32 Pain Relevance 0.12

General Comments

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