INT52795

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Context Info
Confidence 0.38
First Reported 1995
Last Reported 2010
Negated 1
Speculated 0
Reported most in Body
Documents 3
Total Number 3
Disease Relevance 1.58
Pain Relevance 1.77

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoplasm (Btg3)
Anatomy Link Frequency
central nervous system 1
Btg3 (Mus musculus)
Pain Link Frequency Relevance Heat
antinociception 8 100.00 Very High Very High Very High
antagonist 10 99.56 Very High Very High Very High
Opioid 10 99.52 Very High Very High Very High
Central nervous system 3 97.56 Very High Very High Very High
Inflammation 7 94.76 High High
potassium channel 2 92.80 High High
Antinociceptive 4 92.00 High High
rheumatoid arthritis 11 91.96 High High
tail-flick 6 77.60 Quite High
tolerance 3 75.00 Quite High
Disease Link Frequency Relevance Heat
Exanthema 2 97.40 Very High Very High Very High
INFLAMMATION 7 94.76 High High
Rheumatic Diseases 19 94.24 High High
Rheumatoid Arthritis 11 91.96 High High
Disease 30 88.52 High High
Systemic Lupus Erythematosus 28 86.24 High High
Systemic Sclerosis 15 80.32 Quite High
Bordatella Infection 1 69.48 Quite High
Stress 8 61.68 Quite High
Dermatomyositis 5 14.16 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
All these studies demonstrate that a positive ANA test is found frequently in a pediatric hospital population, and even in high titer has only a poor ability to determine whether a child has an inflammatory rheumatic disease.


Regulation (found) of ANA associated with inflammation and rheumatic diseases
1) Confidence 0.38 Published 2010 Journal Pediatr Rheumatol Online J Section Body Doc Link PMC2987328 Disease Relevance 1.45 Pain Relevance 0.23
In contrast to THC, which is blocked by the kappa antagonist nor-binaltorphimine, ANA- and FA-induced antinociception was not altered by classic opioid antagonists.
Neg (not) Regulation (altered) of ANA associated with antinociception, antagonist and opioid
2) Confidence 0.23 Published 1995 Journal J. Pharmacol. Exp. Ther. Section Abstract Doc Link 7791096 Disease Relevance 0.07 Pain Relevance 1.49
The second putative mechanism of B3 gene regulation is related to the effects of glucocorticoid hormones on the central nervous system.


Regulation (regulation) of B3 gene in central nervous system associated with central nervous system
3) Confidence 0.01 Published 2010 Journal Genome Biol Section Body Doc Link PMC2898085 Disease Relevance 0.06 Pain Relevance 0.05

General Comments

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