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Context Info
Confidence 0.11
First Reported 1995
Last Reported 1995
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.17
Pain Relevance 0.61

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Gnrh1) extracellular region (Gnrh1) plasma membrane (Oprd1)
molecular_function (Gnrh1) cytoplasm (Oprd1) signal transducer activity (Oprd1)
Anatomy Link Frequency
pituitary 1
Oprd1 (Rattus norvegicus)
Gnrh1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
agonist 3 100.00 Very High Very High Very High
opioid receptor 2 100.00 Very High Very High Very High
Endogenous opioid 2 95.24 Very High Very High Very High
dexamethasone 4 94.96 High High
Intracerebroventricular 1 67.44 Quite High
antagonist 1 63.24 Quite High
narcan 1 25.00 Low Low
Disease Link Frequency Relevance Heat
Aids-related Complex 2 90.96 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In summary, the present studies show that opioid receptor blockade attenuates systemic, as well as intracerebral inhibitory effects of GR agonists on the GnRH-pituitary LH axis, suggesting that circulating glucocorticoids inhibit LH, in part, through central actions involving endogenous opioid receptors.
opioid receptor Regulation (effects) of GnRH in pituitary associated with endogenous opioid, agonist and opioid receptor
1) Confidence 0.11 Published 1995 Journal Neuropeptides Section Abstract Doc Link 7791961 Disease Relevance 0.17 Pain Relevance 0.61

General Comments

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