INT52865

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Context Info
Confidence 0.49
First Reported 1995
Last Reported 2002
Negated 0
Speculated 0
Reported most in Abstract
Documents 2
Total Number 3
Disease Relevance 0.56
Pain Relevance 2.06

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

mitochondrion (Spr) oxidoreductase activity (Spr) nucleolus (Spr)
nucleus (Spr) cellular_component (Spr) cytoplasm (Spr)
Anatomy Link Frequency
PSNs 3
Spr (Rattus norvegicus)
Pain Link Frequency Relevance Heat
substance P 12 100.00 Very High Very High Very High
Dorsal horn neuron 8 99.20 Very High Very High Very High
Hyperalgesia 4 95.00 High High
parabrachial 3 93.64 High High
Spinal cord 4 91.72 High High
Glutamate 4 82.52 Quite High
Dorsal horn 6 79.84 Quite High
Glutamate receptor 2 77.44 Quite High
nMDA receptor 2 75.00 Quite High
Pain 6 66.56 Quite High
Disease Link Frequency Relevance Heat
Hyperalgesia 4 95.00 High High
Pressure And Volume Under Development 2 94.32 High High
Nociception 3 90.72 High High
Pain 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
By using substance P receptor (SPR) immunofluorescence histochemistry combined with fluorescent retrograde labeling, SPR-like immunoreactive (SPR-LI) neurons sending their axons to the lateral parabrachial region were observed in the lumbar spinal cord of the rat.
Positive_regulation (using) of SPR in neurons associated with spinal cord, parabrachial and substance p
1) Confidence 0.49 Published 1995 Journal Brain Res. Section Abstract Doc Link 7796113 Disease Relevance 0 Pain Relevance 0.28
The up-regulation of SPR and NMDAR mRNAs in DHNs and PSNs was recognized using in situ hybridization and northern blot techniques.
Positive_regulation (up-regulation) of SPR in PSNs associated with dorsal horn neuron
2) Confidence 0.27 Published 2002 Journal Ann. Anat. Section Abstract Doc Link 11876485 Disease Relevance 0.28 Pain Relevance 0.89
The up-regulation of SPR and NMDAR mRNAs in DHNs and PSNs was recognized using in situ hybridization and northern blot techniques.
Positive_regulation (up-regulation) of SPR in DHNs associated with dorsal horn neuron
3) Confidence 0.09 Published 2002 Journal Ann. Anat. Section Abstract Doc Link 11876485 Disease Relevance 0.28 Pain Relevance 0.89

General Comments

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