INT52873

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Context Info
Confidence 0.56
First Reported 1995
Last Reported 2010
Negated 0
Speculated 0
Reported most in Abstract
Documents 4
Total Number 4
Disease Relevance 1.28
Pain Relevance 1.48

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular region (Il1r1) plasma membrane (Il1r1) intracellular (Il1r1)
protein complex (Il1r1) signal transducer activity (Il1r1)
Anatomy Link Frequency
spinal 1
trigeminal ganglion 1
brain 1
dental pulp 1
Il1r1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
trigeminal ganglion 2 98.88 Very High Very High Very High
antagonist 13 96.80 Very High Very High Very High
Inflammation 5 96.32 Very High Very High Very High
Pain 5 92.96 High High
cerebral cortex 1 92.80 High High
cytokine 3 91.88 High High
Lasting pain 2 88.08 High High
Glutamate 2 83.20 Quite High
Trigeminal ganglion neurons 2 75.00 Quite High
Hyperalgesia 2 75.00 Quite High
Disease Link Frequency Relevance Heat
Ganglion Cysts 4 98.44 Very High Very High Very High
INFLAMMATION 5 96.32 Very High Very High Very High
Pain 7 92.96 High High
Nervous System Injury 4 88.84 High High
Hyperalgesia 2 75.00 Quite High
Neuropathic Pain 80 59.92 Quite High
Sleep Disorders 3 5.00 Very Low Very Low Very Low
Nociception 3 5.00 Very Low Very Low Very Low
Vomiting 2 5.00 Very Low Very Low Very Low
Death 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
AIM: To localize interleukin-1 receptor type I (IL-1RI) in rat dental pulp and trigeminal ganglion (TG) and to test the hypothesis that pulpal inflammation increases neuronal expression of IL-1RI.
Localization (localize) of interleukin-1 receptor type I in dental pulp associated with ganglion cysts, inflammation and trigeminal ganglion
1) Confidence 0.56 Published 2009 Journal Int Endod J Section Abstract Doc Link 19732182 Disease Relevance 0.42 Pain Relevance 0.25
Quantitative autoradiographic localization in rat brain of alpha 2-adrenergic and non-adrenergic I-receptor binding sites labelled by [3H]rilmenidine.
Localization (localization) of I-receptor in brain
2) Confidence 0.20 Published 1995 Journal Brain Res. Section Title Doc Link 7796138 Disease Relevance 0 Pain Relevance 0.13
AIM: To localize interleukin-1 receptor type I (IL-1RI) in rat dental pulp and trigeminal ganglion (TG) and to test the hypothesis that pulpal inflammation increases neuronal expression of IL-1RI.
Localization (localize) of interleukin-1 receptor type I in trigeminal ganglion associated with ganglion cysts, inflammation and trigeminal ganglion
3) Confidence 0.19 Published 2009 Journal Int Endod J Section Abstract Doc Link 19732182 Disease Relevance 0.42 Pain Relevance 0.25
Furthermore, it is showed that IL-1R and NR1 are co-localized in spinal neurons [48].
Localization (localized) of IL-1R in spinal
4) Confidence 0.01 Published 2010 Journal Mol Pain Section Body Doc Link PMC2942826 Disease Relevance 0.44 Pain Relevance 0.86

General Comments

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