INT52879

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Context Info
Confidence 0.24
First Reported 1995
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 0.64
Pain Relevance 0.82

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Golgi apparatus (ATP6V0A1) nucleolus (ATP6V0A1) plasma membrane (ATP6V0A1)
nucleus (ATP6V0A1) transmembrane transport (ATP6V0A1) cytoplasm (ATP6V0A1)
Anatomy Link Frequency
erythrocytes 1
osteoclasts 1
ATP6V0A1 (Homo sapiens)
Pain Link Frequency Relevance Heat
adenocard 1 100.00 Very High Very High Very High
lidocaine 8 98.80 Very High Very High Very High
Potency 2 91.32 High High
Bioavailability 1 81.60 Quite High
cva 2 42.12 Quite Low
agonist 2 8.08 Low Low
antagonist 2 6.52 Low Low
rheumatoid arthritis 8 5.00 Very Low Very Low Very Low
alcohol 7 5.00 Very Low Very Low Very Low
Acute pain 4 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Hypercalcemia 19 93.28 High High
Apoptosis 1 90.80 High High
Postmenopausal Osteoporosis 6 70.20 Quite High
Stroke 5 63.24 Quite High
Coronary Artery Disease 8 62.80 Quite High
Death 3 60.88 Quite High
Cardiovascular Disease 1 58.24 Quite High
Breast Cancer 9 52.04 Quite High
Osteoporosis 120 50.00 Quite Low
Thrombosis Related Under Development 2 42.12 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
When erythrocytes were incubated in medium containing bafilomycin A1, an inhibitor of V-ATPase, followed by incubation with lidocaine, the cells changed shape slightly and the intracellular pH showed a small decrease in comparison with control.
Negative_regulation (inhibitor) of V-ATPase in erythrocytes associated with lidocaine
1) Confidence 0.24 Published 1995 Journal Cell Struct. Funct. Section Abstract Doc Link 7796469 Disease Relevance 0 Pain Relevance 0.65
The mechanism of action on osteoclasts includes inhibition of the proton vacuolar adenosine triphosphatase (ATPase) and alteration of the cytoskeleton and the ruffled border.
Negative_regulation (inhibition) of proton vacuolar adenosine triphosphatase in osteoclasts associated with adenocard
2) Confidence 0.01 Published 2008 Journal Osteoporos Int Section Body Doc Link PMC2613968 Disease Relevance 0.64 Pain Relevance 0.17

General Comments

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