INT52910

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Context Info
Confidence 0.19
First Reported 1993
Last Reported 2008
Negated 0
Speculated 0
Reported most in Title
Documents 2
Total Number 2
Disease Relevance 1.03
Pain Relevance 0.66

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

unfolded protein binding (SIL1) protein folding (SIL1) endoplasmic reticulum (SIL1)
SIL1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Morphine 2 100.00 Very High Very High Very High
Cancer pain 1 99.12 Very High Very High Very High
Pain 3 96.16 Very High Very High Very High
Pain score 1 89.36 High High
Nicotine 9 5.00 Very Low Very Low Very Low
Inflammation 5 5.00 Very Low Very Low Very Low
COX-2 inhibitor 1 5.00 Very Low Very Low Very Low
cINOD 1 5.00 Very Low Very Low Very Low
Inflammatory response 1 5.00 Very Low Very Low Very Low
addiction 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cancer Pain 1 99.12 Very High Very High Very High
Pain 4 96.16 Very High Very High Very High
Cancer 41 95.48 Very High Very High Very High
Stress 67 94.52 High High
Apoptosis 8 93.00 High High
Repression 1 92.76 High High
Nicotine Addiction 30 67.20 Quite High
Malignant Neoplastic Disease 20 50.00 Quite Low
Syndrome 2 29.16 Quite Low
Cardiovascular Disease 2 27.60 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Unlike the transcriptionally active ATF6 and XBP1 proteins, PERK, upon release from BiP/GRP78, undergoes autophosphorylation and activation of a kinase function that phosphorylates the alpha subunit of eIF2 (eukaryotic translation initiation factor 2) and a transient repression of global protein synthesis.
Localization (release) of BiP associated with repression
1) Confidence 0.19 Published 2008 Journal BMC Cancer Section Body Doc Link PMC2527015 Disease Relevance 0.47 Pain Relevance 0
Comparison of morphine slow release tablet (MST) and morphine sulphate solution (MSS) in the treatment of cancer pain.
Localization (release) of MSS associated with cancer pain and morphine
2) Confidence 0.18 Published 1993 Journal J Med Assoc Thai Section Title Doc Link 7798818 Disease Relevance 0.56 Pain Relevance 0.66

General Comments

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