INT53022

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Context Info
Confidence 0.65
First Reported 1994
Last Reported 2010
Negated 0
Speculated 1
Reported most in Abstract
Documents 5
Total Number 6
Disease Relevance 4.01
Pain Relevance 0.66

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (CYCS) transport (CYCS) mitochondrion (CYCS)
small molecule metabolic process (CYCS) nucleus (CYCS)
Anatomy Link Frequency
liver 1
CYCS (Homo sapiens)
Pain Link Frequency Relevance Heat
cINOD 4 99.84 Very High Very High Very High
Angina 1 94.36 High High
anesthesia 4 86.40 High High
peptic ulcer disease 1 67.24 Quite High
lidocaine 4 50.00 Quite Low
Cauda equina syndrome 1 5.00 Very Low Very Low Very Low
local anesthetic 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Injury 15 100.00 Very High Very High Very High
INFLAMMATION 2 99.72 Very High Very High Very High
Sprains And Strains 8 99.64 Very High Very High Very High
Cognitive Disorder 3 98.52 Very High Very High Very High
Apoptosis 12 97.84 Very High Very High Very High
Fatigue 1 95.08 Very High Very High Very High
Dyspnea 1 94.72 High High
Angina 1 94.36 High High
Coronary Artery Disease 7 90.80 High High
Gastritis 3 75.00 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Promotion of oxidative damage to arachidonic acid and alpha 1-antiproteinase by anti-inflammatory drugs in the presence of the haem proteins myoglobin and cytochrome C.
Gene_expression (presence) of cytochrome C associated with inflammation and cinod
1) Confidence 0.65 Published 1994 Journal Biochem. Pharmacol. Section Title Doc Link 7811298 Disease Relevance 0.10 Pain Relevance 0.10
The induction of ROS and DNA fragmentation in the mucosal cells in association with these H. pylori strains were assessed by cytochrome c reduction (an index of superoxide anion production), hydroxyl radical production, and DNA fragmentation.
Gene_expression (reduction) of cytochrome c associated with sprains and strains
2) Confidence 0.65 Published 2002 Journal Dig. Dis. Sci. Section Abstract Doc Link 12064819 Disease Relevance 0.99 Pain Relevance 0.07
At low concentrations (3-6 mm) of lidocaine, caspase 3 was activated and release of cytochrome c was detected, whereas at higher concentrations (10 mm), no caspase activation was found.
Gene_expression (detected) of cytochrome c
3) Confidence 0.65 Published 2007 Journal Anesthesiology Section Body Doc Link 17585225 Disease Relevance 0.07 Pain Relevance 0
Innovative technologies such as functional genomics and proteomics have facilitated detection of several promising early biomarkers of AKI, such as neutrophil gelatinase-associated lipocalin (NGAL), cystatin C (CyC), liver-type fatty acid binding protein (L-FABP), interleukin-18 (IL-18), and kidney injury molecule-1 (KIM-1).
Gene_expression (detection) of CyC in liver associated with injury
4) Confidence 0.65 Published 2010 Journal Minerva Anestesiol Section Abstract Doc Link 20473256 Disease Relevance 1.01 Pain Relevance 0.16
Since cytochrome c and its generation of ROS are involved in indomethacin-induced cellular apoptosis, rebamipide may attenuate mitochondrial damage.
Gene_expression (generation) of cytochrome c associated with apoptosis
5) Confidence 0.58 Published 2005 Journal Dig. Dis. Sci. Section Abstract Doc Link 16184425 Disease Relevance 0.79 Pain Relevance 0.24
Statistical analyses produced the Health Complaints Scale (HCS), which comprises 12 somatic and 12 cognitive complaints.
Spec (analyses) Gene_expression (produced) of HCS associated with cognitive disorder
6) Confidence 0.52 Published 1994 Journal Psychosom Med Section Abstract Doc Link 7809347 Disease Relevance 1.04 Pain Relevance 0.09

General Comments

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