INT53035

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Context Info
Confidence 0.43
First Reported 1994
Last Reported 2009
Negated 0
Speculated 0
Reported most in Abstract
Documents 3
Total Number 3
Disease Relevance 0.47
Pain Relevance 0.33

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (Grpr) signal transducer activity (Grpr)
Anatomy Link Frequency
respiratory 1
Grpr (Rattus norvegicus)
Pain Link Frequency Relevance Heat
antagonist 2 98.56 Very High Very High Very High
intrathecal 2 93.52 High High
nMDA receptor 2 75.00 Quite High
Hyperalgesia 1 71.76 Quite High
Glutamate 1 60.00 Quite High
anesthesia 1 25.00 Low Low
qutenza 1 10.00 Low Low
Dopamine 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Nociception 4 97.04 Very High Very High Very High
Pressure And Volume Under Development 1 75.28 Quite High
Hyperalgesia 1 71.76 Quite High
Hypertension 1 30.64 Quite Low
Injury 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The respiratory effects evoked by systemic injection of bombesin were studied in spontaneously breathing rats that were (i) neurally intact and subsequently bilaterally vagotomized, (ii) intact, before and after pharmacological blockade of the bombesin BB(1) and BB(2) receptors.
Negative_regulation (blockade) of bombesin in respiratory
1) Confidence 0.43 Published 2009 Journal Eur. J. Pharmacol. Section Abstract Doc Link 19032952 Disease Relevance 0.08 Pain Relevance 0.03
This effect was abolished by co-administration of [Leu13 psi(CH2NH)-Leu14]bombesin (10 nmol/rat), a bombesin receptor antagonist.
Negative_regulation (co-administration) of bombesin associated with antagonist
2) Confidence 0.37 Published 1994 Journal Eur. J. Pharmacol. Section Abstract Doc Link 7813568 Disease Relevance 0.40 Pain Relevance 0.30
Cyclooxygenase inhibition with indomethacin partially reversed bombesin and mild irritant-induced gastroprotection but did not diminish the protective actions of L-DOPA.
Negative_regulation (reversed) of bombesin
3) Confidence 0.03 Published 1998 Journal Surgery Section Body Doc Link 9823400 Disease Relevance 0 Pain Relevance 0

General Comments

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