INT53066

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Context Info
Confidence 0.49
First Reported 1994
Last Reported 2008
Negated 1
Speculated 0
Reported most in Body
Documents 4
Total Number 4
Disease Relevance 2.38
Pain Relevance 0.95

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (EPO) extracellular space (EPO) aging (EPO)
extracellular region (EPO)
EPO (Homo sapiens)
Pain Link Frequency Relevance Heat
Pain 13 100.00 Very High Very High Very High
visual analogue scale 1 78.60 Quite High
cINOD 4 5.00 Very Low Very Low Very Low
anesthesia 2 5.00 Very Low Very Low Very Low
Central nervous system 1 5.00 Very Low Very Low Very Low
cytokine 1 5.00 Very Low Very Low Very Low
Clonidine 1 5.00 Very Low Very Low Very Low
Inflammation 1 5.00 Very Low Very Low Very Low
tolerance 1 5.00 Very Low Very Low Very Low
headache 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Hypoxia 94 99.84 Very High Very High Very High
Pain 8 97.84 Very High Very High Very High
Sprains And Strains 8 80.88 Quite High
Diuresis 2 76.48 Quite High
Renal Disease 6 72.48 Quite High
Heat Stress Disorders 2 70.92 Quite High
Chronic Renal Failure 10 69.28 Quite High
Weight Gain 4 63.28 Quite High
Proteinuria 2 63.04 Quite High
Vomiting 3 61.56 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Subcutaneous injection of rHuEpo alpha is more painful than rHuEpo beta, even after application of Emla.
Positive_regulation (painful) of Positive_regulation (injection) of rHuEpo associated with pain
1) Confidence 0.49 Published 1994 Journal Nephrol. Dial. Transplant. Section Abstract Doc Link 7816294 Disease Relevance 0.69 Pain Relevance 0.95
As expected, erythropoietin and iron requirements were increased during her pregnancy (erythropoietin from a weekly dose of 6000 to a mean of 14000 units and iron saccharate to 100 mg IV once every week instead of 100 mg/day of oral ferrous fumarate).
Positive_regulation (increased) of Positive_regulation (increased) of erythropoietin
2) Confidence 0.46 Published 2008 Journal J Med Case Reports Section Body Doc Link PMC2278151 Disease Relevance 0.51 Pain Relevance 0
This finding appears to be independent of the duration of rhEpo treatment, as our data showed the same insignificant change in pulmonary V?
Neg (independent) Positive_regulation (independent) of Positive_regulation (duration) of rhEpo
3) Confidence 0.44 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2500186 Disease Relevance 0.74 Pain Relevance 0
Living or training at elevated altitude creates a relative hypoxia, which results in the stimulation of erythropoietin.
Positive_regulation (results) of Positive_regulation (stimulation) of erythropoietin associated with hypoxia
4) Confidence 0.33 Published 2008 Journal Curr Rev Musculoskelet Med Section Body Doc Link PMC2684208 Disease Relevance 0.45 Pain Relevance 0

General Comments

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