INT53150

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Context Info
Confidence 0.74
First Reported 1995
Last Reported 1995
Negated 1
Speculated 2
Reported most in Abstract
Documents 3
Total Number 6
Disease Relevance 0.18
Pain Relevance 2.86

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Scg2) extracellular region (Scg2) intracellular (Scg2)
Anatomy Link Frequency
motor neurons 2
neck 1
motor nerve 1
head 1
Scg2 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Calcitonin gene-related peptide 44 100.00 Very High Very High Very High
tetrodotoxin 16 97.52 Very High Very High Very High
Sciatic nerve 4 97.52 Very High Very High Very High
Neuropeptide 8 95.96 Very High Very High Very High
Neurotransmitter 2 94.96 High High
Spinal cord 6 94.88 High High
substance P 8 85.12 High High
Enkephalin 10 83.52 Quite High
Disease Link Frequency Relevance Heat
Ganglion Cysts 4 92.16 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The expression and content of calcitonin gene-related peptide (CGRP) and secretogranin II (SgII) in adult rat motor neurons were examined by in situ hybridization, Northern blot analysis, and immunocytochemistry.
Spec (examined) Gene_expression (expression) of SgII in motor neurons associated with calcitonin gene-related peptide
1) Confidence 0.74 Published 1995 Journal J. Neurosci. Section Abstract Doc Link 7823160 Disease Relevance 0 Pain Relevance 0.40
No increase in SgII expression was observed.
Gene_expression (expression) of SgII
2) Confidence 0.74 Published 1995 Journal J. Neurosci. Section Abstract Doc Link 7823160 Disease Relevance 0 Pain Relevance 0.79
The expression and content of calcitonin gene-related peptide (CGRP) and secretogranin II (SgII) in adult rat motor neurons were examined by in situ hybridization, Northern blot analysis, and immunocytochemistry.
Spec (examined) Gene_expression (expression) of secretogranin II in motor neurons associated with calcitonin gene-related peptide
3) Confidence 0.74 Published 1995 Journal J. Neurosci. Section Abstract Doc Link 7823160 Disease Relevance 0 Pain Relevance 0.35
Normal motor nerve terminals did not contain detectable CGRP or SgII.
Neg (not) Gene_expression (detectable) of SgII in motor nerve associated with calcitonin gene-related peptide
4) Confidence 0.56 Published 1995 Journal J. Neurosci. Section Abstract Doc Link 7823160 Disease Relevance 0 Pain Relevance 0.60
In this study we examined the possible participation of a novel peptide, secretoneurin (a cleavage product of secretogranin II), in regulation of sympathetic outflow to head and neck by using a retrograde labelling-technique combined with immunohistochemistry.
Gene_expression (product) of secretogranin II in head
5) Confidence 0.24 Published 1995 Journal J. Chem. Neuroanat. Section Abstract Doc Link 8527038 Disease Relevance 0.09 Pain Relevance 0.37
In this study we examined the possible participation of a novel peptide, secretoneurin (a cleavage product of secretogranin II), in regulation of sympathetic outflow to head and neck by using a retrograde labelling-technique combined with immunohistochemistry.
Gene_expression (product) of secretogranin II in neck
6) Confidence 0.08 Published 1995 Journal J. Chem. Neuroanat. Section Abstract Doc Link 8527038 Disease Relevance 0.09 Pain Relevance 0.37

General Comments

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