INT53152

Context Info Confidence 0.03 First Reported 1995 Last Reported 1995 Negated 1 Speculated 0 Reported most in Abstract Documents 1 Total Number 1 Disease Relevance 0 Pain Relevance 0.90

intracellular (Rac1, Scg2) enzyme binding (Rac1) GTPase activity (Rac1) cytoplasm (Rac1) cell proliferation (Rac1) extracellular space (Scg2)

Anatomy Link Frequency motor neurons 1 Rac1 (Rattus norvegicus) Scg2 (Rattus norvegicus)

Pain Link Frequency Relevance Heat Calcitonin gene-related peptide 11 100.00 tetrodotoxin 4 99.88 Sciatic nerve 1 94.76 Spinal cord 1 92.12

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Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

Nerve blocks by tetrodotoxin (TTX) and botulinum toxin (BoTX) increased CGRP content and expression in motor neurons but had no effect on SgII.

botulinum toxin Neg (no) Regulation (effect) of SgII in motor neurons associated with tetrodotoxin and calcitonin gene-related peptide

1) Confidence 0.03 Published 1995 Journal J. Neurosci. Section Abstract Doc Link 7823160 Disease Relevance 0 Pain Relevance 0.90

General Comments

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