INT53218

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Context Info
Confidence 0.03
First Reported 1994
Last Reported 2007
Negated 0
Speculated 0
Reported most in Title
Documents 2
Total Number 2
Disease Relevance 0.54
Pain Relevance 0.58

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

mitochondrion (Decr1) oxidoreductase activity (Decr1) nucleus (Decr1)
cytoplasm (Decr1)
Anatomy Link Frequency
dorsal horn 2
Decr1 (Mus musculus)
Pain Link Frequency Relevance Heat
Dorsal horn 13 100.00 Very High Very High Very High
cINOD 2 99.98 Very High Very High Very High
Hippocampus 1 93.52 High High
Spinal cord 7 89.60 High High
dexamethasone 1 84.00 Quite High
tetrodotoxin 1 83.88 Quite High
Pain 2 39.76 Quite Low
unmyelinated 4 23.48 Low Low
c fibre 1 19.48 Low Low
diabetic neuropathy 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Injury 5 100.00 Very High Very High Very High
INFLAMMATION 2 99.86 Very High Very High Very High
Diabetes Mellitus 24 66.16 Quite High
Hyperglycemia 9 50.00 Quite Low
Syndrome 1 41.20 Quite Low
Chronic Disease 1 38.64 Quite Low
Diabetic Neuropathy 3 37.36 Quite Low
Apoptosis 1 27.56 Quite Low
Targeted Disruption 6 5.00 Very Low Very Low Very Low
Congenital Anomalies 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Our results suggest that in addition to the pathological state that led to our observed loss of sensory neurons (and diminished NADPH-d labeling in the dorsal horn), there is a ongoing perturbation resulting in increased NADPH-d labeling in small DRG neurons from hyperglycemic animals as compared to the primary sensory somata from normoglycemic animals.
Negative_regulation (diminished) of Positive_regulation (increased) of NADPH-d in dorsal horn associated with dorsal horn
1) Confidence 0.03 Published 2007 Journal J Brachial Plex Peripher Nerve Inj Section Body Doc Link PMC1865541 Disease Relevance 0.16 Pain Relevance 0.31
Anti-inflammatory drugs suppress injury-induced NADPH-d activity in CA1 pyramidal neurones.
Negative_regulation (suppress) of Positive_regulation (induced) of NADPH-d associated with inflammation, injury and cinod
2) Confidence 0.01 Published 1994 Journal Neuroreport Section Title Doc Link 7827327 Disease Relevance 0.38 Pain Relevance 0.28

General Comments

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