INT53236

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Context Info
Confidence 0.40
First Reported 1994
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 5
Total Number 5
Disease Relevance 3.84
Pain Relevance 1.41

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Anatomy Link Frequency
pituitary 2
brachial plexus 2
Il1 (Mus musculus)
Pain Link Frequency Relevance Heat
Inflammation 92 100.00 Very High Very High Very High
medulla 30 100.00 Very High Very High Very High
rheumatoid arthritis 80 99.80 Very High Very High Very High
cytokine 70 98.28 Very High Very High Very High
Spinal cord 25 92.72 High High
Hippocampus 1 82.32 Quite High
Deafferentation 1 78.56 Quite High
Nerve growth factor 1 59.28 Quite High
Central nervous system 4 57.68 Quite High
Inflammatory mediators 1 54.80 Quite High
Disease Link Frequency Relevance Heat
INFLAMMATION 86 100.00 Very High Very High Very High
Cold Sores 72 100.00 Very High Very High Very High
Crystal Associated Disease 5 99.82 Very High Very High Very High
Rheumatoid Arthritis 82 99.80 Very High Very High Very High
Stress 15 98.60 Very High Very High Very High
Urological Neuroanatomy 1 97.88 Very High Very High Very High
Cryopyrin-associated Periodic Syndromes 10 79.04 Quite High
Alzheimer's Dementia 1 78.08 Quite High
Disease 34 72.80 Quite High
Diabetes Mellitus 5 69.92 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In contrast, [125I]interleukin-1 (IL-1)alpha binding was significantly increased in the pituitary at 2 h after the stress and tended to be higher than non-stressed levels at 6 h after the stress but was not statistically significant.
Positive_regulation (increased) of IL-1 Binding (binding) of in pituitary associated with stress
1) Confidence 0.40 Published 1994 Journal Brain Res. Section Abstract Doc Link 7827996 Disease Relevance 0.90 Pain Relevance 0.04
Notably, we found that the changes occur after brachial plexus avulsion is relatively specific in the brainstem, IL-1?
Positive_regulation (specific) of IL-1 Binding (brainstem) of in brachial plexus associated with medulla
2) Confidence 0.11 Published 2010 Journal J Brachial Plex Peripher Nerve Inj Section Body Doc Link PMC3017042 Disease Relevance 0.13 Pain Relevance 0.31
Chlorhexidine (CHX) caused a less marked increase in HSV susceptibility and only statistically insignificant trends in Il-1?
Positive_regulation (increase) of Il-1 Binding (trends) of associated with cold sores
3) Confidence 0.06 Published 2006 Journal BMC Infect Dis Section Body Doc Link PMC1523343 Disease Relevance 0.93 Pain Relevance 0.61
RA FLS were stimulated with either recombinant human IL-1?
Positive_regulation (stimulated) of IL-1 Binding (recombinant) of associated with rheumatoid arthritis
4) Confidence 0.06 Published 2010 Journal Arthritis Res Ther Section Body Doc Link PMC2888198 Disease Relevance 0.67 Pain Relevance 0.26
The concept of reversing gout crystal-induced inflammation with IL-1?
Positive_regulation (induced) of IL-1 Binding (inflammation) of associated with inflammation and crystal associated disease
5) Confidence 0.05 Published 2010 Journal Curr Allergy Asthma Rep Section Body Doc Link PMC2892083 Disease Relevance 1.20 Pain Relevance 0.18

General Comments

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