INT53291

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Context Info
Confidence 0.10
First Reported 1995
Last Reported 2010
Negated 1
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 0.67
Pain Relevance 1.02

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (OPN1LW) plasma membrane (OPN1LW) signal transducer activity (OPN1LW)
Anatomy Link Frequency
1A2 2
OPN1LW (Homo sapiens)
Pain Link Frequency Relevance Heat
carbamazepine 213 100.00 Very High Very High Very High
Pain 101 98.48 Very High Very High Very High
Trigeminal neuralgia 44 81.28 Quite High
Inflammation 1 57.24 Quite High
Analgesic 14 55.20 Quite High
local anesthetic 7 50.00 Quite Low
Gabapentin 16 27.40 Quite Low
antidepressant 3 12.76 Low Low
fifth nerve 4 5.00 Very Low Very Low Very Low
Multiple sclerosis 4 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Pain 107 98.48 Very High Very High Very High
Neuralgia 45 81.28 Quite High
INFLAMMATION 1 57.24 Quite High
Adhesions 1 56.60 Quite High
Demyelinating Disease 6 5.00 Very Low Very Low Very Low
Hypersensitivity 4 5.00 Very Low Very Low Very Low
Cancer 3 5.00 Very Low Very Low Very Low
Depression 2 5.00 Very Low Very Low Very Low
Ganglion Cysts 2 5.00 Very Low Very Low Very Low
Neuropathic Pain 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Clinical impact of the CBZ + ROP association
Negative_regulation (impact) of ROP Binding (association) of associated with carbamazepine
1) Confidence 0.10 Published 2010 Journal Journal of pain research Section Body Doc Link PMC3004633 Disease Relevance 0.67 Pain Relevance 1.02
Anti CYP3A2 and 1A2 antibodies inhibited the formation of PPX and 3'-OH Rop in human hepatic microsomes, respectively.
Negative_regulation (inhibited) of Rop Neg (inhibited) Binding (formation) of in 1A2
2) Confidence 0.03 Published 1995 Journal Anesthesiology Section Body Doc Link 7832304 Disease Relevance 0 Pain Relevance 0

General Comments

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