INT53383

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Context Info
Confidence 0.45
First Reported 1994
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 3
Total Number 4
Disease Relevance 0.86
Pain Relevance 0.48

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleoplasm (NR1D2) nucleus (NR1D2)
NR1D2 (Homo sapiens)
Pain Link Frequency Relevance Heat
Inflammation 2 89.36 High High
medulla 4 83.12 Quite High
cINOD 3 76.72 Quite High
Paracetamol 1 73.60 Quite High
anesthesia 10 65.56 Quite High
Opioid 2 23.92 Low Low
cva 4 5.00 Very Low Very Low Very Low
Calcium channel 4 5.00 Very Low Very Low Very Low
Catecholamine 4 5.00 Very Low Very Low Very Low
ischemia 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
INFLAMMATION 5 89.36 High High
Adhesions 5 86.40 High High
Acute Renal Failure 3 80.24 Quite High
Stress 2 74.00 Quite High
Hypoxia 3 73.72 Quite High
Renal Disease 18 67.16 Quite High
Aneurism 6 61.64 Quite High
Hypertension 2 57.20 Quite High
Cv Unclassified Under Development 4 53.28 Quite High
Increased Venous Pressure Under Development 14 48.60 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Using analysis of variance for repeated measures, indomethacin produced a significant reduction in RBF compared with control (P = 0.009) that was associated with a significant elevation in RVR (P = 0.027).
Positive_regulation (elevation) of RVR
1) Confidence 0.45 Published 1994 Journal Med Sci Sports Exerc Section Abstract Doc Link 7837949 Disease Relevance 0.15 Pain Relevance 0.21
In summary, MgSO4 30 mg/kg over 3 min immediately before aortic unclamping followed by an infusion of 10 mg/kg/hr attenuated the increase in RVR and improves RCBF after aortic unclamping in dogs.
Positive_regulation (increase) of RVR
2) Confidence 0.43 Published 2005 Journal Journal of Korean Medical Science Section Body Doc Link PMC2782157 Disease Relevance 0.19 Pain Relevance 0.11
This result may suggest that the administration of MgSO4 prevents the increase in RVR and improves the RCBF after the aortic unclamping.
Positive_regulation (increase) of RVR
3) Confidence 0.43 Published 2005 Journal Journal of Korean Medical Science Section Body Doc Link PMC2782157 Disease Relevance 0.26 Pain Relevance 0.04
activates the nuclear hormone receptor nuclear receptor subfamily 1, group D, member 2 (NR1D2), blocking signaling from the orphan receptor-?
Positive_regulation (activates) of NR1D2
4) Confidence 0.39 Published 2008 Journal Environ Health Perspect Section Body Doc Link PMC2290973 Disease Relevance 0.26 Pain Relevance 0.12

General Comments

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