INT53486

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Context Info
Confidence 0.34
First Reported 1994
Last Reported 2004
Negated 1
Speculated 1
Reported most in Abstract
Documents 6
Total Number 7
Disease Relevance 4.21
Pain Relevance 1.75

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell differentiation (Stmn1) cytosol (Stmn1) cytoskeleton (Stmn1)
intracellular (Stmn1) cytoplasm (Stmn1)
Anatomy Link Frequency
brainstem 1
epithelium 1
nervous system 1
Stmn1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
opioid receptor 7 99.96 Very High Very High Very High
medulla 5 99.26 Very High Very High Very High
Chronic pancreatitis 6 95.00 High High
orphanin 12 92.00 High High
Opioid 4 87.36 High High
Morphine 5 87.28 High High
agonist 4 75.00 Quite High
antagonist 4 75.00 Quite High
Dynorphin 1 73.04 Quite High
cINOD 2 50.00 Quite Low
Disease Link Frequency Relevance Heat
Cancer 15 100.00 Very High Very High Very High
Hyperplasia 9 99.80 Very High Very High Very High
Malignant Neoplastic Disease 18 99.76 Very High Very High Very High
Pancreatic Cancer 3 95.36 Very High Very High Very High
Pancreatitis 6 95.00 High High
Colon Cancer 3 93.20 High High
Apoptosis 2 91.96 High High
Aids-related Complex 1 86.20 High High
Carcinoma 3 81.92 Quite High
Neuroblastoma 1 53.04 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
With the exception of Gap43, the levels of Cltc, Gfap, Tau, stathmin, and alpha-tubulin proteins were found to be in good agreement with those from mRNA quantification.
Gene_expression (levels) of stathmin
1) Confidence 0.34 Published 2004 Journal Neuropsychopharmacology Section Abstract Doc Link 15199374 Disease Relevance 0.09 Pain Relevance 0.37
The OP4 receptor is widely expressed in the nervous system where it mediates a broad range of physiological functions.
Gene_expression (expressed) of OP4 in nervous system
2) Confidence 0.02 Published 1999 Journal Farmaco Section Abstract Doc Link 10668183 Disease Relevance 0 Pain Relevance 0.73
Cultured cells from the rat brainstem were used to study opioid receptor (OpR) expression during late fetal and early postnatal development.
Gene_expression (expression) of OpR in brainstem associated with medulla and opioid receptor
3) Confidence 0.01 Published 2004 Journal Brain Res. Dev. Brain Res. Section Abstract Doc Link 15013624 Disease Relevance 0.05 Pain Relevance 0.26
The expression of c-erbB-2 oncoprotein and cellular proliferation marker Ki67 was less common in malignant lesions, but was absent in the benign cases.
Neg (absent) Gene_expression (expression) of oncoprotein associated with malignant neoplastic disease and hyperplasia
4) Confidence 0.01 Published 1994 Journal Anticancer Res. Section Abstract Doc Link 7847827 Disease Relevance 1.40 Pain Relevance 0.16
Expression of p53 tumor suppressor gene, oncoprotein c-erbB-2, cellular proliferation and differentiation in malignant and benign pancreatic lesions.
Gene_expression (Expression) of oncoprotein associated with malignant neoplastic disease, cancer and hyperplasia
5) Confidence 0.01 Published 1994 Journal Anticancer Res. Section Title Doc Link 7847827 Disease Relevance 1.37 Pain Relevance 0.15
The expression of oncoprotein, tumor suppressor gene, cellular proliferation and differentiation markers were studied in 64 malignant and benign pancreatic tumors, adjacent and distant to the tumor duct epithelium.
Gene_expression (expression) of oncoprotein in epithelium associated with malignant neoplastic disease, cancer, pancreatic cancer and hyperplasia
6) Confidence 0.01 Published 1994 Journal Anticancer Res. Section Abstract Doc Link 7847827 Disease Relevance 1.12 Pain Relevance 0.08
The expression of c-myc oncoprotein and p53 and p27 suppressor proteins was examined using the immunocytochemical method.
Spec (examined) Gene_expression (expression) of oncoprotein
7) Confidence 0.01 Published 2001 Journal J. Cancer Res. Clin. Oncol. Section Body Doc Link 11260862 Disease Relevance 0.19 Pain Relevance 0

General Comments

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